LNX1 anticorps (AA 101-200) (AbBy Fluor® 488)
-
- Antigène Voir toutes LNX1 Anticorps
- LNX1 (Ligand of Numb-Protein X 1 (LNX1))
-
Épitope
- AA 101-200
-
Reactivité
- Souris, Rat
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp LNX1 est conjugé à/à la AbBy Fluor® 488
-
Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Souris, Rat
- Homologie
- Human,Cow,Sheep,Horse
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human LNX1
- Isotype
- IgG
- Top Product
- Discover our top product LNX1 Anticorps primaire
-
-
- Indications d'application
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
-
- Antigène
- LNX1 (Ligand of Numb-Protein X 1 (LNX1))
- Autre désignation
- LNX1 (LNX1 Produits)
- Synonymes
- anticorps LNX1, anticorps fj78f06, anticorps lnx, anticorps si:dkey-12h2.1, anticorps wu:fj78f06, anticorps zgc:152906, anticorps Lnx, anticorps LNX, anticorps MPDZ, anticorps PDZRN2, anticorps ligand of numb-protein X 1, anticorps LNX1, anticorps lnx1, anticorps Lnx1
- Sujet
-
Synonyms: E3 ubiquitin protein ligase LNX, Ligand of Numb protein X 1, Ligand of numb protein X 1 E3 ubiquitin protein ligase, LNX, LNX1, LNX1_HUMAN, MPDZ, Multi PDZ domain containing protein E3 ubiquitin protein ligase LNX, Numb binding protein 1, PDZ domain-containing ring finger protein 2, PDZRN2.
Background: Lnx1 is a membrane-bound protein that is involved in signal transduction and protein interactions. Lnx1 is an E3 Ubiquitin ligase protein that mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Lnx1 mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65.
- ID gène
- 84708
- UniProt
- Q8TBB1
-