PKC iota anticorps (AA 181-280) (AbBy Fluor® 647)
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- Antigène Voir toutes PKC iota (PRKCI) Anticorps
- PKC iota (PRKCI) (Protein Kinase C, iota (PRKCI))
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Épitope
- AA 181-280
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PKC iota est conjugé à/à la AbBy Fluor® 647
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Réactivité croisée
- Humain, Souris
- Homologie
- Rat,Cow,Sheep,Pig,Horse
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human PKC iota/PKCI
- Isotype
- IgG
- Top Product
- Discover our top product PRKCI Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- PKC iota (PRKCI) (Protein Kinase C, iota (PRKCI))
- Autre désignation
- PKC iota (PRKCI Produits)
- Synonymes
- anticorps DXS1179E, anticorps PKCI, anticorps nPKC-iota, anticorps aPKC[l], anticorps hal, anticorps has, anticorps PRKCI, anticorps PKC, anticorps 2310021H13Rik, anticorps AI427505, anticorps PKClambda, anticorps Pkci, anticorps Pkcl, anticorps Prkcl, anticorps aPKClambda, anticorps mKIAA4165, anticorps protein kinase C iota, anticorps protein kinase C, iota, anticorps PRKCI, anticorps prkci, anticorps Prkci
- Sujet
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Synonyms: aPKC lambda/iota, aPKC-lambda/iota, Atypical protein kinase C lambda/iota, Atypical protein kinase C-lambda/iota, DXS1179E, KPCI_HUMAN, MGC26534, nPKC iota, nPKC-iota, nPKCiota, PKC lambda, PKCI, PKCiota, PKClambda, PRKC iota, PRKC lambda/iota, PRKC-lambda/iota, PRKCI, Protein kinase C iota, Protein kinase C iota type.
Background: This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. There is a single exon pseudogene mapped on chromosome X. [provided by RefSeq, Jul 2008]
- ID gène
- 5584
- UniProt
- P41743
- Pathways
- Neurotrophin Signaling Pathway, Cell-Cell Junction Organization, Tube Formation
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