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Importin 8 anticorps (AA 1-100) (AbBy Fluor® 647)

IPO8 Reactivité: Rat IF (cc), IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 647
N° du produit ABIN6980266
  • Antigène Voir toutes Importin 8 (IPO8) Anticorps
    Importin 8 (IPO8)
    Épitope
    • 14
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    Reactivité
    • 18
    • 16
    • 4
    • 2
    • 2
    • 2
    • 1
    Rat
    Hôte
    • 32
    • 1
    • 1
    Lapin
    Clonalité
    • 33
    • 1
    Polyclonal
    Conjugué
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Importin 8 est conjugé à/à la AbBy Fluor® 647
    Application
    • 12
    • 12
    • 9
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Rat
    Homologie
    Human,Mouse,Cow,Sheep,Pig
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Importin 8
    Isotype
    IgG
    Top Product
    Discover our top product IPO8 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Importin 8 (IPO8)
    Autre désignation
    Importin 8 (IPO8 Produits)
    Synonymes
    anticorps IPO8, anticorps si:ch211-116i17.1, anticorps RANBP8, anticorps 6230418K12Rik, anticorps Abcc10, anticorps C130009K11Rik, anticorps MRP7, anticorps OM-1, anticorps Om1, anticorps Ranbp8, anticorps importin 8, anticorps IPO8, anticorps ipo8, anticorps Ipo8
    Sujet

    Synonyms: FLJ26580, Imp 8, Imp8, Importin-8, Importin8, IPO 8, IPO8, IPO8_HUMAN, Ran binding protein 8, RAN BP8, Ran-binding protein 8, RANBP 8, RANBP8.

    Background: Seems to function in nuclear protein import, either by acting as autonomous nuclear transport receptor or as an adapter-like protein in association with the importin-beta subunit KPNB1. Acting autonomously, is thought to serve itself as receptor for nuclear localization signals (NLS) and to promote translocation of import substrates through the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. In vitro mediates the nuclear import of SRP19.

    ID gène
    10526
    UniProt
    O15397
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