DBNL anticorps (AA 201-300) (AbBy Fluor® 647)
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- Antigène Voir toutes DBNL Anticorps
- DBNL (Drebrin-Like (DBNL))
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Épitope
- AA 201-300
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Reactivité
- Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DBNL est conjugé à/à la AbBy Fluor® 647
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Souris
- Homologie
- Human
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human HIP55
- Isotype
- IgG
- Top Product
- Discover our top product DBNL Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- DBNL (Drebrin-Like (DBNL))
- Autre désignation
- HIP55 (DBNL Produits)
- Synonymes
- anticorps ABP1, anticorps HIP-55, anticorps HIP55, anticorps SH3P7, anticorps Abp1, anticorps mAbp1, anticorps Sh3p7, anticorps abp1, anticorps dbnl-B, anticorps DBNL, anticorps DKFZp459C0939, anticorps drebrin like, anticorps drebrin-like, anticorps drebrin like S homeolog, anticorps drebrin 1, anticorps DBNL, anticorps Dbnl, anticorps dbnl.S, anticorps LOC100148204, anticorps DBN1
- Sujet
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Synonyms: ABP1, Actin-binding protein 1, Cervical mucin associated protein, Cervical mucin-associated protein, Cervical SH3P7, CMAP, Dbnl, DBNL_HUMAN, Drebrin F, drebrin like, Drebrin like protein, Drebrin-F, Drebrin-like protein, HIP 55, HIP-55, HPK1 interacting protein of 55 kDa, HPK1-interacting protein of 55 kDa, SH3 domain containing protein 7, SH3 domain-containing protein 7, SH3P7, Src Homology 3 Domain Containing Protein, src homology 3 domain containing protein HIP
Background: Adapter protein that binds F-actin and DNM1, and thereby plays a role in receptor-mediated endocytosis. Plays a role in the reorganization of the actin cytoskeleton, formation of cell projections, such as neurites, in neuron morphogenesis and synapse formation via its interaction with WASL and COBL. Does not bind G-actin and promote actin polymerization by itself. Required for the formation of organized podosome rosettes (By similarity). May act as a common effector of antigen receptor-signaling pathways in leukocytes. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes.
- ID gène
- 28988
- UniProt
- Q9UJU6
- Pathways
- TCR Signaling, Regulation of Actin Filament Polymerization
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