NEK6 anticorps (AA 81-180) (AbBy Fluor® 647)
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- Antigène Voir toutes NEK6 Anticorps
- NEK6 (NIMA (Never in Mitosis Gene A)-Related Kinase 6 (NEK6))
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Épitope
- AA 81-180
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Reactivité
- Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NEK6 est conjugé à/à la AbBy Fluor® 647
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Rat
- Homologie
- Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human NEK6
- Isotype
- IgG
- Top Product
- Discover our top product NEK6 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- NEK6 (NIMA (Never in Mitosis Gene A)-Related Kinase 6 (NEK6))
- Autre désignation
- NEK6 (NEK6 Produits)
- Synonymes
- anticorps 1300007C09Rik, anticorps si:ch211-167p9.4, anticorps ATNEK5, anticorps MOE17.17, anticorps NIMA-RELATED KINASE5, anticorps NIMA-related kinase 5, anticorps SID6-1512, anticorps NIMA (never in mitosis gene a)-related expressed kinase 6, anticorps NIMA-related kinase 6, anticorps NIMA related kinase 6, anticorps Serine/Threonine kinase catalytic domain protein, anticorps NIMA-related kinase 6 S homeolog, anticorps Nek6, anticorps nek6, anticorps NEK6, anticorps NEK5, anticorps nek6.S
- Sujet
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Synonyms: Highly similar to cell cycle protein kinase CDC5/MSD2, NEK6, NEK6_HUMAN, Never in mitosis A-related kinase 6, NIMA (Never In Mitosis Gene A) Related Kinase 6, NimA related protein kinase 6, NimA-related protein kinase 6, Protein kinase SID6 1512, Protein kinase SID6-1512, Putative serine threonine protein kinase, Serine/threonine protein kinase Nek6, Serine/threonine-protein kinase Nek6, SID61512.
Background: Protein kinase which plays an important role in mitotic cell cycle progression. Required for chromosome segregation at metaphase-anaphase transition, robust mitotic spindle formation and cytokinesis. Phosphorylates ATF4, CIR1, PTN, RAD26L, RBBP6, RPS7, RPS6KB1, TRIP4, STAT3 and histones H1 and H3. Phosphorylates KIF11 to promote mitotic spindle formation. Involved in G2/M phase cell cycle arrest induced by DNA damage. Inhibition of activity results in apoptosis. May contribute to tumorigenesis by suppressing p53/TP53-induced cancer cell senescence.
- ID gène
- 10783
- UniProt
- Q9HC98
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