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STK24 anticorps (pThr178) (Biotin)

STK24 Reactivité: Souris, Rat WB, ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN6982572
  • Antigène Voir toutes STK24 Anticorps
    STK24 (serine/threonine Kinase 24 (STK24))
    Épitope
    • 14
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr178
    Reactivité
    • 59
    • 35
    • 28
    • 1
    • 1
    • 1
    • 1
    Souris, Rat
    Hôte
    • 64
    • 9
    Lapin
    Clonalité
    • 64
    • 9
    Polyclonal
    Conjugué
    • 24
    • 7
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp STK24 est conjugé à/à la Biotin
    Application
    • 55
    • 35
    • 18
    • 13
    • 13
    • 10
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Souris, Rat
    Homologie
    Human,Cow,Sheep,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthesised phosphopeptide derived from human MST3 around the phosphorylation site of Thr178
    Isotype
    IgG
    Top Product
    Discover our top product STK24 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    STK24 (serine/threonine Kinase 24 (STK24))
    Autre désignation
    MST3 (STK24 Produits)
    Synonymes
    anticorps MST3, anticorps MST3B, anticorps STE20, anticorps STK3, anticorps 1810013H02Rik, anticorps C76483, anticorps MST-3, anticorps Mst3, anticorps Mst3b, anticorps RGD1561742, anticorps stk24, anticorps wu:fi29b08, anticorps zgc:66137, anticorps 0610042I06Rik, anticorps MST, anticorps Mst2, anticorps Ste20, anticorps mess1, anticorps zgc:163071, anticorps mst3, anticorps mst3b, anticorps ste20, anticorps stk3, anticorps serine/threonine kinase 24, anticorps serine/threonine kinase 24b (STE20 homolog, yeast), anticorps serine/threonine-protein kinase 24, anticorps serine/threonine kinase 3, anticorps serine/threonine kinase 24a (STE20 homolog, yeast), anticorps serine/threonine kinase 24 L homeolog, anticorps STK24, anticorps Stk24, anticorps stk24b, anticorps ATEG_04314, anticorps ATEG_09179, anticorps UREG_03984, anticorps BDBG_07988, anticorps MCYG_07323, anticorps Stk3, anticorps stk24a, anticorps stk24.L
    Sujet

    Synonyms: MST3 (phospho T178), p-MST3 (phospho T178), Kinase responsive to stress 1, KRS1, Mammalian STE20 like protein kinase 2, Mammalian sterile 20-like 2, Mess1, MST, MST-2, MST2, Mst3, Serine/threonine kinase 3 (STE20 homolog, yeast), Serine/threonine kinase 3 (Ste20, yeast homolog), Serine/threonine protein kinase 3, Serine/threonine protein kinase Krs1, STE20 like kinase MST2.

    Background: Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress-induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase-independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on 'Thr-442' and stimulates its kinase activity. Regulates cellular migration with alteration of PTPN12 activity and PXN phosphorylation: phosphorylates PTPN12 and inhibits its activity and may regulate PXN phosphorylation through PTPN12. May act as a key regulator of axon regeneration in the optic nerve and radial nerve.

    ID gène
    8428
    UniProt
    Q9Y6E0
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