LNX1 anticorps (AA 101-200) (Biotin)

N° du produit ABIN6982670

Détail du produit anti-LNX1 anticorps (Biotin)

Antigène: LNX1 (Ligand of Numb-Protein X 1 (LNX1))

Épitope: AA 101-200

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LNX1 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Souris, Rat

Homologie: Human,Cow,Sheep,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human LNX1

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur LNX1

Antigène: LNX1 (Ligand of Numb-Protein X 1 (LNX1))

Autre désignation: LNX1 (LNX1 Produits)

Synonymes: anticorps LNX1, anticorps fj78f06, anticorps lnx, anticorps si:dkey-12h2.1, anticorps wu:fj78f06, anticorps zgc:152906, anticorps Lnx, anticorps LNX, anticorps MPDZ, anticorps PDZRN2, anticorps ligand of numb-protein X 1, anticorps LNX1, anticorps lnx1, anticorps Lnx1

Sujet:

Synonyms: E3 ubiquitin protein ligase LNX, Ligand of Numb protein X 1, Ligand of numb protein X 1 E3 ubiquitin protein ligase, LNX, LNX1, LNX1_HUMAN, MPDZ, Multi PDZ domain containing protein E3 ubiquitin protein ligase LNX, Numb binding protein 1, PDZ domain-containing ring finger protein 2, PDZRN2.

Background: Lnx1 is a membrane-bound protein that is involved in signal transduction and protein interactions. Lnx1 is an E3 Ubiquitin ligase protein that mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Lnx1 mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65.

ID gène: 84708

UniProt: Q8TBB1