TUBA1B anticorps (AA 401-451) (Biotin)

N° du produit ABIN6982747

Détail du produit anti-TUBA1B anticorps (Biotin)

Antigène: TUBA1B (Tubulin, alpha 1B (TUBA1B))

Épitope: AA 401-451

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TUBA1B est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TUBA1A + TUBA1B

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur TUBA1B

Antigène: TUBA1B (Tubulin, alpha 1B (TUBA1B))

Autre désignation: TUBA1A + TUBA1B (TUBA1B Produits)

Synonymes: anticorps RGD1565476, anticorps K-ALPHA-1, anticorps cb944, anticorps fb22g06, anticorps tuba1, anticorps wu:fb22g06, anticorps Tuba2, anticorps TUBA3, anticorps k-alpha-1, anticorps tuba, anticorps Calpha1, anticorps Tuba1, anticorps TUBA1B, anticorps tubulin, alpha 1B, anticorps tubulin alpha 1b, anticorps tubulin, alpha 1b, anticorps tubulin alpha 1b L homeolog, anticorps tubulin alpha-1B chain, anticorps Tubulin alpha-1B chain, anticorps Tuba1b, anticorps TUBA1B, anticorps tuba1b, anticorps tuba1b.L, anticorps LOC100445003, anticorps LOC102178700

Sujet:

Synonyms: TUBA1A + TUBA1B, Tubulin, Alpha 1b, Tubulin Alpha-Ubiquitous Chain, Alpha-Tubulin Ubiquitous, Tubulin K-Alpha-1, Tubulin, Alpha, Ubiquitous, Tubulin Alpha-1B Chain, Alpha Tubulin, Ubiquitous, K-ALPHA-1, Tubulin Alpha, TBA1B_HUMAN, Tubulin, Alpha 1a, TUBA3, Tubulin Alpha-3 Chain, Tubulin B-Alpha-1, LIS3, Tubulin, Alpha, Brain-Specific, Tubulin Alpha-1A Chain, Alpha-Tubulin 3, Brain-Specific, Hum-A-Tub1, Hum-A-Tub2, B-ALPHA-1, TBA1A_HUMAN, ,____alpha

Background: Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q. Mutations in this gene cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly, mental retardation, and early-onset epilepsy and caused by defective neuronal migration. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012]

ID gène: 7846

UniProt: Q71U36

Pathways: Dynamique des Microtubules, M Phase