MAP3K9 anticorps (AA 231-330) (Biotin)

N° du produit ABIN6982829

Détail du produit anti-MAP3K9 anticorps (Biotin)

Antigène: MAP3K9 (Mitogen-Activated Protein Kinase Kinase Kinase 9 (MAP3K9))

Épitope: AA 231-330

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP3K9 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris

Homologie: Rat,Dog,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MAP3K9

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur MAP3K9

Antigène: MAP3K9 (Mitogen-Activated Protein Kinase Kinase Kinase 9 (MAP3K9))

Autre désignation: MAP3K9 (MAP3K9 Produits)

Synonymes: anticorps MEKK9, anticorps MLK1, anticorps PRKE1, anticorps E130314H24Rik, anticorps Mlk1, anticorps Prke1, anticorps RGD1562149, anticorps mitogen-activated protein kinase kinase kinase 9, anticorps MAP3K9, anticorps Map3k9

Sujet:

Synonyms: MLK1, M3K9_HUMAN, Map3k9, MEKK9, Mitogen activated protein kinase kinase kinase 9, Mitogen-activated protein kinase kinase kinase 9, Mixed lineage kinase 1 (tyr and ser/thr specificity), Mixed lineage kinase 1, PRKE1.

Background: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade through the phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7 which in turn activate the JNKs. The MKK/JNK signaling pathway regulates stress response via activator protein-1 (JUN) and GATA4 transcription factors. Plays also a role in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis.

ID gène: 4293

UniProt: P80192