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ZIC2 anticorps (AA 131-230) (Biotin)

ZIC2 Reactivité: Rat, Souris IHC (p) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN6982884
  • Antigène Voir toutes ZIC2 Anticorps
    ZIC2
    Épitope
    • 15
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 131-230
    Reactivité
    • 18
    • 16
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Rat, Souris
    Hôte
    • 31
    • 2
    • 1
    Lapin
    Clonalité
    • 32
    • 2
    Polyclonal
    Conjugué
    • 12
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ZIC2 est conjugé à/à la Biotin
    Application
    • 24
    • 13
    • 13
    • 8
    • 6
    • 3
    • 3
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Souris, Rat
    Homologie
    Human,Cow,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Zic2
    Isotype
    IgG
    Top Product
    Discover our top product ZIC2 Anticorps primaire
  • Indications d'application
    IHC-P 1:200-400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    ZIC2
    Autre désignation
    Zic2 (ZIC2 Produits)
    Synonymes
    anticorps HPE5, anticorps Ku, anticorps cb851, anticorps fb26a03, anticorps wu:fb26a03, anticorps zic2, anticorps zic2.1, anticorps hpe5, anticorps hm:zeh0655, anticorps id:ibd5017, anticorps zic2.2, anticorps zic2l, anticorps Zic family member 2, anticorps zinc finger protein of the cerebellum 2, anticorps zic family member 2 (odd-paired homolog, Drosophila), a, anticorps Zic family member 2 L homeolog, anticorps zic family member 2 (odd-paired homolog, Drosophila) b, anticorps ZIC2, anticorps Zic2, anticorps zic2a, anticorps zic2.L, anticorps zic2b
    Sujet

    Synonyms: HPE 5, HPE5, Odd paired homolog Drosophila, Zic 2, Zic family member 2 (odd paired Drosophila homolog), Zic family member 2, ZIC2, ZIC2_HUMAN, Zinc finger protein of the cerebellum 2, Zinc finger protein ZIC 2, Zinc finger protein Zic2.

    Background: Acts as a transcriptional activator or repressor. Plays important roles in the early stage of organogenesis of the CNS. Activates the transcription of the serotonin transporter SERT in uncrossed ipsilateral retinal ganglion cells (iRGCs) to refine eye-specific projections in primary visual targets. Its transcriptional activity is repressed by MDFIC. Involved in the formation of the ipsilateral retinal projection at the optic chiasm midline. Drives the expression of EPHB1 on ipsilaterally projecting growth cones. Binds to the minimal GLI-consensus sequence 5'-TGGGTGGTC-3'. Associates to the basal SERT promoter region from ventrotemporal retinal segments of retinal embryos.

    ID gène
    7546
    UniProt
    O95409
    Pathways
    Tube Formation
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