VPS4B anticorps (AA 301-400) (Cy3)
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- Antigène Voir toutes VPS4B (vps4b) Anticorps
- VPS4B (vps4b) (Vacuolar Protein Sorting 4 Homolog B (vps4b))
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Épitope
- AA 301-400
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Reactivité
- Humain, Souris, Poisson
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp VPS4B est conjugé à/à la Cy3
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Poisson, Humain, Souris
- Homologie
- Rat,Cow,Pig
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human VPS4B
- Isotype
- IgG
- Top Product
- Discover our top product vps4b Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- VPS4B (vps4b) (Vacuolar Protein Sorting 4 Homolog B (vps4b))
- Autre désignation
- VPS4B (vps4b Produits)
- Synonymes
- anticorps zgc:63682, anticorps vps4a, anticorps SKD1, anticorps SKD1B, anticorps VPS4-2, anticorps 8030489C12Rik, anticorps Skd1, anticorps vacuolar protein sorting 4 homolog B, anticorps vacuolar protein sorting 4 homolog B S homeolog, anticorps vacuolar protein sorting 4b homolog B (S. cerevisiae), anticorps vacuolar protein sorting 4 homolog B (S. cerevisiae), anticorps vacuolar protein sorting 4B, anticorps Vps4b, anticorps vps4b.S, anticorps vps4b, anticorps VPS4B
- Sujet
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Synonyms: 8030489C12Rik, Cell migration inducing 1, Cell migration-inducing gene 1 protein, MGC116271, MIG1, Protein SKD1, Skd1, SKD1B, Suppressor of K(+) transport growth defect 1, Suppressor of K+ transport defect 1, Vacuolar protein sorting 4 homolog B (S. cerevisiae), Vacuolar protein sorting 4 homolog B, Vacuolar protein sorting 4b, Vacuolar protein sorting-associated protein 4B, Vacuolar protein sorting-associating protein 4B, VPS4 2, VPS42, Vps4b, VPS4B_HUMAN.
Background: Involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane fission. Redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. In conjunction with the ESCRT machinery also appears to function in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses).
- ID gène
- 9525
- UniProt
- O75351
- Pathways
- Dynamique des Microtubules, CXCR4-mediated Signaling Events
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