KLHL18 anticorps (AA 451-550) (Cy3)

N° du produit ABIN6983423

Détail du produit anti-KLHL18 anticorps (Cy3)

Antigène: KLHL18 (Kelch-Like 18 (KLHL18))

Épitope: AA 451-550

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLHL18 est conjugé à/à la Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Rat

Homologie: Mouse,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human KLHL18

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur KLHL18

Antigène: KLHL18 (Kelch-Like 18 (KLHL18))

Autre désignation: KLHL18 (KLHL18 Produits)

Synonymes: anticorps A930041K15, anticorps AW545966, anticorps kelch-like 18, anticorps kelch like family member 18, anticorps Klhl18, anticorps KLHL18

Sujet:

Synonyms: Kelch-like protein 18, KLHL18, KIAA0795, OK/SW-cl.74

Background: KLHL18 is a 574 amino acid protein that is related to the Drosophila kelch protein, which is required to maintain actin organization in ovarian ring canals. Mutations affecting Kelch function result in failure of Kelch to associate with the ring canals and subsequent female sterility. Human KLHL18 protein contains six kelch repeats, one BACK (BTB/Kelch associated) domain and one BTB (POZ) domain. The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. There are two isoforms of KLHL18 that are produced as a result of alternative splicing events.

ID gène: 23276

UniProt: O94889