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MED12 anticorps (AA 251-350) (Cy3)

MED12 Reactivité: Souris, Rat WB, IF (cc), IF (p) Hôte: Lapin Polyclonal Cy3
N° du produit ABIN6983572
  • Antigène Voir toutes MED12 Anticorps
    MED12 (Mediator Complex Subunit 12 (MED12))
    Épitope
    • 14
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 251-350
    Reactivité
    • 28
    • 24
    • 16
    • 1
    • 1
    • 1
    • 1
    Souris, Rat
    Hôte
    • 38
    • 1
    • 1
    Lapin
    Clonalité
    • 39
    • 1
    Polyclonal
    Conjugué
    • 17
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MED12 est conjugé à/à la Cy3
    Application
    • 24
    • 15
    • 12
    • 12
    • 8
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Souris, Rat
    Homologie
    Human,Cow,Sheep,Pig,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human MED12/Trap230
    Isotype
    IgG
    Top Product
    Discover our top product MED12 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    MED12 (Mediator Complex Subunit 12 (MED12))
    Autre désignation
    MED12/Trap230 (MED12 Produits)
    Synonymes
    anticorps ARC240, anticorps CAGH45, anticorps FGS1, anticorps HOPA, anticorps MED12S, anticorps OHDOX, anticorps OKS, anticorps OPA1, anticorps TNRC11, anticorps TRAP230, anticorps 230kDa, anticorps Mopa, anticorps OPA-1, anticorps Tnrc11, anticorps Trap230, anticorps mediator complex subunit 12, anticorps MED12, anticorps Med12, anticorps med12
    Sujet

    Synonyms: Mediator of RNA polymerase II transcription subunit 12, MED12, Activator-recruited cofactor 240 kDa component, ARC240, CAG repeat protein 45 Mediator complex subunit 12, OPA-containing protein, Thyroid hormone receptor-associated protein complex 230 kDa component, Trap230, Trinucleotide repeat-containing gene 11 protein, MED12, ARC240, CAGH45, HOPA, KIAA0192, TNRC11, TRAP230

    Background: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway.

    ID gène
    9968
    UniProt
    Q93074
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Tube Formation
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