TTC3 anticorps (AA 251-350)
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- Antigène Voir toutes TTC3 Anticorps
- TTC3 (Tetratricopeptide Repeat Domain 3 (TTC3))
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Épitope
- AA 251-350
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Reactivité
- Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TTC3 est non-conjugé
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Réactivité croisée
- Souris, Rat
- Homologie
- Human
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human RNF105
- Isotype
- IgG
- Top Product
- Discover our top product TTC3 Anticorps primaire
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- Indications d'application
- IHC-P 1:200-400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- TTC3 (Tetratricopeptide Repeat Domain 3 (TTC3))
- Autre désignation
- RNF105 (TTC3 Produits)
- Synonymes
- anticorps DCRR1, anticorps RNF105, anticorps TPRDIII, anticorps 2610202A04Rik, anticorps AA409221, anticorps D16Ium21, anticorps D16Ium21e, anticorps TPRD, anticorps mKIAA4119, anticorps TTC3, anticorps tetratricopeptide repeat domain 3, anticorps E3 ubiquitin-protein ligase TTC3, anticorps TTC3, anticorps Ttc3, anticorps LOC100562480
- Sujet
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Synonyms: DCRR1, E3 ubiquitin protein ligase TTC3, E3 ubiquitin-protein ligase TTC3, Protein DCRR1, RING finger protein 105,Tetratricopeptide repeat protein 3 (TPR repeat protein D), Tetratricopeptide repeat protein 3, TPR repeat protein 3, TPR repeat protein D, TPRD, TPRDI, TPRDII, TPRDIII, TTC3, TTC3_HUMAN.
Background: E3 ubiquitin-protein ligase that mediates the ubiquitination and subsequent degradation of phosphorylated Akt (AKT1, AKT2 and AKT3) in the nucleus. Acts as a terminal regulator of Akt signaling after activation, its phosphorylation by Akt, which is a prerequisite for ubiquitin ligase activity, suggests the existence of a regulation mechanism required to control Akt levels after activation. Catalyzes the formation of 'Lys-48'-polyubiquitin chains. May play a role in neuronal differentiation inhibition via its interaction with CIT.
- ID gène
- 7267
- UniProt
- P53804
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