STK24 anticorps (pThr178)

N° du produit ABIN6989149

Détail du produit anti-STK24 anticorps

Antigène: STK24 (serine/threonine Kinase 24 (STK24))

Épitope: pThr178

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STK24 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Souris, Rat

Homologie: Human,Cow,Sheep,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthesised phosphopeptide derived from human MST3 around the phosphorylation site of Thr178

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur STK24

Antigène: STK24 (serine/threonine Kinase 24 (STK24))

Autre désignation: MST3 (STK24 Produits)

Synonymes: anticorps MST3, anticorps MST3B, anticorps STE20, anticorps STK3, anticorps 1810013H02Rik, anticorps C76483, anticorps MST-3, anticorps Mst3, anticorps Mst3b, anticorps RGD1561742, anticorps stk24, anticorps wu:fi29b08, anticorps zgc:66137, anticorps 0610042I06Rik, anticorps MST, anticorps Mst2, anticorps Ste20, anticorps mess1, anticorps zgc:163071, anticorps mst3, anticorps mst3b, anticorps ste20, anticorps stk3, anticorps serine/threonine kinase 24, anticorps serine/threonine kinase 24b (STE20 homolog, yeast), anticorps serine/threonine-protein kinase 24, anticorps serine/threonine kinase 3, anticorps serine/threonine kinase 24a (STE20 homolog, yeast), anticorps serine/threonine kinase 24 L homeolog, anticorps STK24, anticorps Stk24, anticorps stk24b, anticorps ATEG_04314, anticorps ATEG_09179, anticorps UREG_03984, anticorps BDBG_07988, anticorps MCYG_07323, anticorps Stk3, anticorps stk24a, anticorps stk24.L

Sujet:

Synonyms: MST3 (phospho T178), p-MST3 (phospho T178), Kinase responsive to stress 1, KRS1, Mammalian STE20 like protein kinase 2, Mammalian sterile 20-like 2, Mess1, MST, MST-2, MST2, Mst3, Serine/threonine kinase 3 (STE20 homolog, yeast), Serine/threonine kinase 3 (Ste20, yeast homolog), Serine/threonine protein kinase 3, Serine/threonine protein kinase Krs1, STE20 like kinase MST2.

Background: Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress-induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase-independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on 'Thr-442' and stimulates its kinase activity. Regulates cellular migration with alteration of PTPN12 activity and PXN phosphorylation: phosphorylates PTPN12 and inhibits its activity and may regulate PXN phosphorylation through PTPN12. May act as a key regulator of axon regeneration in the optic nerve and radial nerve.

ID gène: 8428

UniProt: Q9Y6E0