SYNCRIP anticorps (AA 51-150)

N° du produit ABIN6989206

Détail du produit anti-SYNCRIP anticorps

Antigène: SYNCRIP (Synaptotagmin Binding, Cytoplasmic RNA Interacting Protein (SYNCRIP))

Épitope: AA 51-150

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SYNCRIP est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Souris, Rat

Homologie: Human,Cow,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human hnRNP Q

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur SYNCRIP

Antigène: SYNCRIP (Synaptotagmin Binding, Cytoplasmic RNA Interacting Protein (SYNCRIP))

Autre désignation: hnRNP Q (SYNCRIP Produits)

Synonymes: anticorps GRY-RBP, anticorps GRYRBP, anticorps HNRNPQ, anticorps HNRPQ1, anticorps NSAP1, anticorps PP68, anticorps hnRNP-Q, anticorps 2610109K23Rik, anticorps 4632417O19Rik, anticorps Nsap1, anticorps Nsap1l, anticorps pp68, anticorps nsap1, anticorps wu:fe02c03, anticorps wu:fe47h09, anticorps SYNCRIP, anticorps hnrpq1, anticorps gry-rbp, anticorps rp1-3j17.2, anticorps synaptotagmin binding cytoplasmic RNA interacting protein, anticorps synaptotagmin binding, cytoplasmic RNA interacting protein, anticorps synaptotagmin binding cytoplasmic RNA interacting protein S homeolog, anticorps SYNCRIP, anticorps Syncrip, anticorps syncrip, anticorps syncrip.S

Sujet:

Synonyms: cytoplasmic RNA-interacting protein, dJ3J17.2, Glycine and tyrosine rich RNA binding protein, Glycine- and tyrosine-rich RNA-binding protein, GRY RBP, GRY-RBP, Heterogeneous nuclear ribonucleoprotein Q, hnRNP Q, HNRPQ 1, HNRPQ, HNRPQ_HUMAN, HNRPQ1, NS1 associated protein 1, NS1-associated protein 1, NSAP 1, NSAP1, pp68, RP1 3J17.2, Synaptotagmin binding cytoplasmic RNA interacting protein, Synaptotagmin-binding, SYNCRIP.

Background: Heterogenous nuclear ribonucleoprotein (hnRNP) implicated in mRNA processing mechanisms. Component of the CRD-mediated complex that promotes MYC mRNA stability. Isoform 1, isoform 2 and isoform 3 are associated in vitro with pre-mRNA, splicing intermediates and mature mRNA protein complexes. Isoform 1 binds to apoB mRNA AU-rich sequences. Isoform 1 is part of the APOB mRNA editosome complex and may modulate the postranscriptional C to U RNA-editing of the APOB mRNA through either by binding to A1CF (APOBEC1 complementation factor), to APOBEC1 or to RNA itself. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Interacts in vitro preferentially with poly(A) and poly(U) RNA sequences. Isoform 3 may be involved in cytoplasmic vesicle-based mRNA transport through interaction with synaptotagmins.

ID gène: 10492

UniProt: O60506