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ALKBH5 anticorps (AA 1-100)

ALKBH5 Reactivité: Souris, Rat ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6989272
  • Antigène Voir toutes ALKBH5 Anticorps
    ALKBH5 (AlkB, Alkylation Repair Homolog 5 (ALKBH5))
    Épitope
    • 14
    • 7
    • 7
    • 6
    • 6
    • 2
    • 1
    AA 1-100
    Reactivité
    • 26
    • 23
    • 16
    Souris, Rat
    Hôte
    • 38
    • 2
    Lapin
    Clonalité
    • 40
    Polyclonal
    Conjugué
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ALKBH5 est non-conjugé
    Application
    • 19
    • 17
    • 12
    • 12
    • 3
    • 2
    • 1
    • 1
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
     Réactivité croisée
    Souris, Rat
    Homologie
    Human,Dog,Cow,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human ALKBH5
    Isotype
    IgG
    Top Product
    Discover our top product ALKBH5 Anticorps primaire
  • Indications d'application
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    ALKBH5 (AlkB, Alkylation Repair Homolog 5 (ALKBH5))
    Autre désignation
    ALKBH5 (ALKBH5 Produits)
    Synonymes
    anticorps RGD1309496, anticorps ABH5, anticorps OFOXD, anticorps OFOXD1, anticorps AW050020, anticorps AW215868, anticorps Abh5, anticorps E130207K11, anticorps Ofoxd, anticorps alkB homolog 5, RNA demethylase, anticorps alkB homolog 5, RNA demethylase L homeolog, anticorps Alkbh5, anticorps alkbh5.L, anticorps ALKBH5
    Sujet

    Synonyms: ABH5, AlkB, alkylation repair homolog 5 (E. coli), AlkB, alkylation repair homolog 5, Alkylated DNA repair protein alkB homolog 5, Alpha ketoglutarate dependent dioxygenase alkB homolog 5, OFOXD, OFOXD1, Oxoglutarate and iron-dependent oxygenase domain containing, Probable alpha ketoglutarate dependent dioxygenase ABH5, RNA demethylase ALKBH5.

    Background: Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6)-methyladenosine (m6A)RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes (PubMed:23177736, PubMed:24778178,PubMed:24616105, PubMed:24489119). Can also demethylate N(6)-methyladenosine in single-stranded DNA (in vitro)(PubMed:24616105). Requires molecular oxygen, alpha-ketoglutarate and iron (PubMed:21264265, PubMed:23177736, PubMed:24778178,PubMed:24616105, PubMed:24489119). Demethylation of m6A mRNA affects mRNA processing and export (PubMed:23177736). Required for spermatogenesis (By similarity).

    ID gène
    54890
    UniProt
    Q6P6C2
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