KDM1B anticorps (AA 51-150)

N° du produit ABIN6989407

Détail du produit anti-KDM1B anticorps

Antigène: KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))

Épitope: AA 51-150

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KDM1B est non-conjugé

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human LSD2 / AOF1

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur KDM1B

Antigène: KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))

Autre désignation: LSD2 / AOF1 (KDM1B Produits)

Synonymes: anticorps AOF1, anticorps C6orf193, anticorps LSD2, anticorps bA204B7.3, anticorps dJ298J15.2, anticorps 4632428N09Rik, anticorps AI482520, anticorps Aof1, anticorps lysine demethylase 1B, anticorps lysine-specific histone demethylase 1B, anticorps lysine (K)-specific demethylase 1B, anticorps KDM1B, anticorps LOC577549, anticorps kdm1b, anticorps Kdm1b

Sujet:

Synonyms: LSD2 / AOF1, KDM1B, amine oxidase (flavin containing) domain 1, amine oxidase, flavin containing 1, AOF1, bA204B7.3, C6orf193, dJ298J15.2, Flavin-containing amine oxidase domain-containing protein 1, FLJ33898, FLJ34109, FLJ43328, KDM1B, KDM1B_HUMAN, LSD2, lysine (K)-specific demethylase 1B, Lysine-specific demethylase 2, Lysine-specific histone demethylase 1B, Lysine-specific histone demethylase 2.

Background: Histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. Has no effect on tri-methylated 'Lys-4', mono-, di- or tri-methylated 'Lys-9', mono-, di- or tri-methylated 'Lys-27', mono-, di- or tri-methylated 'Lys-36' of histone H3, or on mono-, di- or tri-methylated 'Lys-20' of histone H4.

ID gène: 221656

UniProt: Q8NB78

Pathways: L'effet Warburg