NOTCH4 anticorps (AA 1151-1250)

N° du produit ABIN6989410

Détail du produit anti-NOTCH4 anticorps

Antigène: NOTCH4 (Notch 4 (NOTCH4))

Épitope: AA 1151-1250

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NOTCH4 est non-conjugé

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human NOTCH4

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur NOTCH4

Antigène: NOTCH4 (Notch 4 (NOTCH4))

Autre désignation: NOTCH4 (NOTCH4 Produits)

Synonymes: anticorps INT3, anticorps NOTCH3, anticorps Int-3, anticorps Int3, anticorps N4, anticorps Notch4, anticorps notch 4, anticorps neurogenic locus notch homolog protein 4, anticorps NOTCH4, anticorps Notch4, anticorps LOC100712850

Sujet:

Synonyms: Notch 4, FLJ16302, hNotch 4, hNotch4, INT 3, INT3, MGC74442, Neurogenic locus notch homolog protein 4, NOTC4_HUMAN, NOTCH 3, NOTCH 4, Notch 4 intracellular domain, Notch homolog 4, NOTCH3, Notch4, NOTCH4 protein, OTTHUMP00000062678.

Background: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system.

ID gène: 4855

UniProt: Q99466

Pathways: Signalisation Notch