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MCFD2 anticorps (AA 1-100)

MCFD2 Reactivité: Rat, Souris WB, IF (cc), IF (p), IHC (p), IHC (fro), ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6989560
  • Antigène Voir toutes MCFD2 Anticorps
    MCFD2 (Multiple Coagulation Factor Deficiency 2 (MCFD2))
    Épitope
    • 14
    • 7
    • 2
    • 1
    • 1
    AA 1-100
    Reactivité
    • 26
    • 22
    • 21
    Rat, Souris
    Hôte
    • 29
    • 11
    Lapin
    Clonalité
    • 30
    • 10
    Polyclonal
    Conjugué
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MCFD2 est non-conjugé
    Application
    • 27
    • 15
    • 12
    • 12
    • 8
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
     Réactivité croisée
    Souris, Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from mouse MCFD2
    Isotype
    IgG
    Top Product
    Discover our top product MCFD2 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    MCFD2 (Multiple Coagulation Factor Deficiency 2 (MCFD2))
    Autre désignation
    MCFD2 (MCFD2 Produits)
    Synonymes
    anticorps hm:zeh1186, anticorps wu:fc23b10, anticorps wu:fd50d08, anticorps zgc:103713, anticorps zgc:109915, anticorps MCFD2, anticorps DKFZp469B098, anticorps F5F8D, anticorps F5F8D2, anticorps LMAN1IP, anticorps SDNSF, anticorps 1810021C21Rik, anticorps F5f8d, anticorps Lman1ip, anticorps Sdnsf, anticorps multiple coagulation factor deficiency 2, anticorps multiple coagulation factor deficiency 2 L homeolog, anticorps MCFD2, anticorps mcfd2, anticorps mcfd2.L, anticorps Mcfd2
    Sujet

    Synonyms: 1810021C21Rik, DKFZp686G21263, F5F8D, LMAN1IP, MCFD 2, Mcfd2, MCFD2_MOUSE, Multiple coagulation factor deficiency protein 2, Neural stem cell derived neuronal survival protein, Neural stem cell-derived neuronal survival protein, SDNSF.

    Background: This gene encodes a soluble luminal protein with two calmodulin-like EF-hand motifs at its C-terminus. This protein forms a complex with LAMN1 (lectin mannose binding protein 1, also known as ERGIC-53) that facilitates the transport of coagulation factors V (FV) and VIII (FVIII) from the endoplasmic reticulum to the Golgi apparatus via an endoplasmic reticulum Golgi intermediate compartment (ERGIC). Mutations in this gene cause combined deficiency of FV and FVIII (F5F8D), a rare autosomal recessive bleeding disorder characterized by mild to moderate bleeding and coordinate reduction in plasma FV and FVIII levels. This protein has also been shown to maintain stem cell potential in adult central nervous system and is a marker for testicular germ cell tumors. The 3' UTR of this gene contains a transposon-like human repeat element named 'THE 1'. A processed RNA pseudogene of this gene is on chromosome 6p22.1. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jun 2010]

    ID gène
    193813
    UniProt
    Q8K5B2
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