HLA-F anticorps
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- Antigène Voir toutes HLA-F (HLAF) Anticorps
- HLA-F (HLAF) (HLA Class I alpha F (HLAF))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp HLA-F est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Réactivité croisée
- Humain
- Purification
- Purified by Protein A.
- Immunogène
- Synthetic Peptide corresponding to C terminal human HLA F.
- Clone
- 4H
- Isotype
- IgG
- Top Product
- Discover our top product HLAF Anticorps primaire
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- Indications d'application
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WB 1:300-5000
IHC-P 1:200-400 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C for 12 months.
- Date de péremption
- 12 months
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- Antigène
- HLA-F (HLAF) (HLA Class I alpha F (HLAF))
- Autre désignation
- HLA F (HLAF Produits)
- Synonymes
- anticorps HLAF, anticorps CDA12, anticorps HLA-5.4, anticorps HLA-CDA12, anticorps major histocompatibility complex, class I, F, anticorps HLA-F
- Sujet
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Synonyms: CDA12 antibody, HLA 5.4 antibody, HLA class I histocompatibility antigen, alpha chain F antibody, HLA class I molecule antibody, HLA F antigen antibody, HLA-CDA12 antibody, HLA-F antibody, HLAF antibody, HLAF_HUMAN antibody, Leukocyte antigen F antibody, MHC class I antigen F antibody
Background: This gene belongs to the HLA class I heavy chain paralogues. It encodes a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. This gene exhibits few polymorphisms. Multiple transcript variants encoding different isoforms have been found for this gene. These variants lack a coding exon found in transcripts from other HLA paralogues due to an altered splice acceptor site, resulting in a shorter cytoplasmic domain. [provided by RefSeq, Jul 2008]
- ID gène
- 3134
- UniProt
- P30511
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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