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kappa Light Chain anticorps

Reactivité: Humain WB, IHC (p) Hôte: Lapin Monoclonal 9B1 unconjugated
N° du produit ABIN6989724
  • Antigène Voir toutes kappa Light Chain Anticorps
    kappa Light Chain
    Reactivité
    • 33
    • 19
    • 1
    Humain
    Hôte
    • 24
    • 23
    • 2
    • 1
    • 1
    Lapin
    Clonalité
    • 26
    • 25
    Monoclonal
    Conjugué
    • 13
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp kappa Light Chain est non-conjugé
    Application
    • 30
    • 23
    • 13
    • 13
    • 10
    • 9
    • 9
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain
    Purification
    Purified by Protein A.
    Immunogène
    Full length native human IgG.
    Clone
    9B1
    Isotype
    IgG
    Top Product
    Discover our top product kappa Light Chain Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    kappa Light Chain
    Abstract
    kappa Light Chain Produits
    Synonymes
    anticorps LOC100037688, anticorps B128L, anticorps B55L, anticorps IgK, anticorps TCRAV31S1, anticorps TCRAV40S1, anticorps kappa light chain, anticorps immunoglobulin kappa chain variable 8 (V8), anticorps T cell receptor alpha variable 40, anticorps LOC100037688, anticorps Igk-V8, anticorps TRAV40
    Sujet

    Synonyms: Kappa Light Chain, IGKC, HCAK 1, HCAK1, Ig kappa chain C region, IGKC, Immunoglobulin kappa constant, Immunoglobulin kappa constant region, Immunoglobulin kappa light chain, Kappa 1 immunoglobulin light chain, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809, Human Ig/L-Chain Kappa, IGKC_HUMAN.

    Background: Immunoglobulins belong to a group of related glyco proteins which make up 20 % of serum proteins. Antigens and immunoglobulins react to confer immunity to individuals. Immunoglobulins have similar structures of two identical heavy chains and two identical light chains. Both the heavy chains and the light chains are divided into constant and variable regions. The constant regions have the same amino acid sequences between all the immunoglobulin classes. The variable regions have approximately 110 amino acids with high sequence variability. The amino acid sequence of the heavy chain determines the class of an immunoglobulin. The five types of immunoglobulin heavy chains are known as: IgG, IgA, IgM, IgD, and IgE. IgG is divided into four subclasses, and IgA is divided into two subclasses. In serum IgA and IgG are monomers with a single 4 polypeptide unit, while, IgM is a pen tamer. IgA may also form polymers.
    Kappa light chain antibody can be used for the identification of leukemias, plasmacytomas and certain non Hodgkin's lymphomas. Kappa light chain contains one immunoglobulin like domain. The EU sequence has the INV allotypic marker, Ala 45 and Val 83. The ROY sequence has the INV allotypic marker, Ala 45 and Leu 83.

    ID gène
    3514
    UniProt
    P01834
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