CDK8 anticorps
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- Antigène Voir toutes CDK8 Anticorps
- CDK8 (Cyclin-Dependent Kinase 8 (CDK8))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CDK8 est non-conjugé
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Application
- Western Blotting (WB), Immunoprecipitation (IP)
- Réactivité croisée
- Humain, Souris, Rat
- Purification
- Purified by Protein A.
- Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 365-464 of human CDK8 (NP_001251.1).
- Isotype
- IgG
- Top Product
- Discover our top product CDK8 Anticorps primaire
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- Indications d'application
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WB 1:300-5000
IP(1-2 μg) - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C for 12 months.
- Date de péremption
- 12 months
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- Antigène
- CDK8 (Cyclin-Dependent Kinase 8 (CDK8))
- Autre désignation
- CDK8 (CDK8 Produits)
- Sujet
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Synonyms: CDK8,K35
Background: This gene encodes a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit, cyclin C, are components of the Mediator transcriptional regulatory complex, involved in both transcriptional activation and repression by phosphorylation of the carboxy-terminal domain of the largest subunit of RNA polymerase II. This kinase regulates transcription by targeting the cyclin-dependent kinase 7 subunits of the general transcription initiation factor IIH, thus providing a link between the Mediator complex and the basal transcription machinery. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.
- ID gène
- 1024
- UniProt
- P49336
- Pathways
- Cycle Cellulaire, Regulation of Lipid Metabolism by PPARalpha
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