CHRAC1 anticorps
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- Antigène Voir toutes CHRAC1 Anticorps
- CHRAC1 (Chromatin Accessibility Complex 1 (CHRAC1))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CHRAC1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Réactivité croisée
- Humain, Souris, Rat
- Purification
- Purified by Protein A.
- Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-131 of human CHRAC1 (NP_059140.1).
- Isotype
- IgG
- Top Product
- Discover our top product CHRAC1 Anticorps primaire
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- Indications d'application
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WB 1:300-5000
IHC() - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C for 12 months.
- Date de péremption
- 12 months
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- Antigène
- CHRAC1 (Chromatin Accessibility Complex 1 (CHRAC1))
- Autre désignation
- CHRAC1 (CHRAC1 Produits)
- Sujet
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Synonyms: CHRAC1,CHARC1,CHARC15,CHRAC-1,CHRAC-15,CHRAC15,YCL1
Background: DNA replication is initiated by the binding of initiation factors to the origin of replication. Nucleosomes inhibit access to the replication machinery at these origin sequences. Nucleosome remodeling factors increase the accessibility of nucleosomal DNA to transcriptional regulators (1). CHRAC15 and CHRAC17 are subunits of the nucleosomal remodeling factor CHRAC (chromatin accessibility complex),which increases the accessibility of nucleosomal DNA in an ATP-dependent manner (2). Unlike other known chromatin remodelling factors, CHRAC also functions during chromatin assembly by using ATP to convert irregular chromatin into a regular array of nucleosomes with even spacing (3). This conversion process occurs when CHRAC organizes randomly deposited histones into a regularly spaced array (4). In the presence of CHRAC, the nucleosomal ATPase ISWI catalyses several ATP-dependent transitions of chromatin structure (5).
- ID gène
- 54108
- UniProt
- Q9NRG0
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