EGLN1 anticorps

N° du produit ABIN6989779

Détail du produit anti-EGLN1 anticorps

Antigène: EGLN1 (Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EGLN1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-426 of human EGLN1 (NP_071334.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200
IHC()
IF()

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur EGLN1

Antigène: EGLN1 (Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1))

Autre désignation: EGLN1 (EGLN1 Produits)

Synonymes: anticorps EGLN1, anticorps egln2, anticorps phd2, anticorps zgc:92314, anticorps AI503754, anticorps C1orf12, anticorps HIF-PH2, anticorps HPH-2, anticorps Hif-p4h-2, anticorps ORF13, anticorps Phd2, anticorps SM-20, anticorps PHD-2, anticorps PHD2, anticorps ECYT3, anticorps HIFPH2, anticorps HPH2, anticorps SM20, anticorps ZMYND6, anticorps egl nine homolog 1 (C. elegans), anticorps egl-9 family hypoxia inducible factor 1, anticorps egl-9 family hypoxia-inducible factor 1 S homeolog, anticorps egl-9 family hypoxia-inducible factor 1b, anticorps egl-9 family hypoxia-inducible factor 1, anticorps EGLN1, anticorps egln1.S, anticorps egln1b, anticorps Egln1

Sujet:

Synonyms: EGLN1,C1orf12,ECYT3,HALAH,HIF-PH2,HIFPH2,HPH-2,HPH2,PHD2,SM20,ZMYND6

Background: The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3).

ID gène: 54583

UniProt: Q9GZT9

Pathways: cAMP Metabolic Process, L'effet Warburg