SARS-CoV-2 Spike S1 anticorps

N° du produit ABIN6990098

Détail du produit anti-SARS-CoV-2 Spike S1 anticorps

Antigène: SARS-CoV-2 Spike S1

Reactivité: SARS Coronavirus-2 (SARS-CoV-2)

Hôte: Human

Clonalité: Monoclonal

Conjugué: Cet anticorp SARS-CoV-2 Spike S1 est non-conjugé

Application: ELISA

Specificité: Antibody recognizes 2019-nCoV S1 Protein/ 2019-nCoV S-RBD Protein.

Pureté: 95,00%

Immunogène: Cultured in vitro under conditions free from animal derived components.

Clone: 5D9

Isotype: IgG1

Information d'application

Indications d'application: Immunoreactivity: 80-120 % compared to the reference sample in an ELISA test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2.0 mg/mL

Buffer: PBS, pH 7.4

Stock: -20 °C,4 °C

Stockage commentaire: 24 months from manufacturing at <-20 °C, 1 month, 2 to 8 °C under sterile conditions.

Détails sur SARS-CoV-2 Spike S1

Antigène: SARS-CoV-2 Spike S1

Autre désignation: SARS-CoV-2 S1 (SARS-CoV-2 Spike S1 Produits)

Synonymes: anticorps E2, anticorps Surface Glycoprotein, anticorps S

Classe de substances: Viral Protein

Sujet: The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

ID gène: 43740568