GFRA3 anticorps

N° du produit ABIN6990252

Détail du produit anti-GFRA3 anticorps

Antigène: GFRA3 (GDNF Family Receptor alpha 3 (GFRA3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GFRA3 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: GFR alpha 3 Antibody is Antibody is DEAE purified.

Immunogène: GFR alpha 3 antibody was raised against a 14 amino acid peptide near the center of murine GFR alpha 3. The immunogen is located within the last 50 amino acids of GFR alpha 3.

Isotype: IgG

Information d'application

Indications d'application: GFR alpha 3 antibody can be used for detection of GFR alpha 3 expression by Western blot at 0.5 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: GFR alpha 3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: GFR alpha 3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur GFRA3

Antigène: GFRA3 (GDNF Family Receptor alpha 3 (GFRA3))

Autre désignation: GFR alpha 3 (GFRA3 Produits)

Synonymes: anticorps GFRA3, anticorps GFRalpha3, anticorps Y15110, anticorps GDNF family receptor alpha 3, anticorps glial cell line derived neurotrophic factor family receptor alpha 3, anticorps Gfra3, anticorps GFRA3

Sujet: GFR alpha 3 Antibody: Members of the glial cell line-derived neurotrophic factor (GDNF) family, including GDNF and neurturin (NTN) play essential roles in the control of vertebrate neuron survival and differentiation. A new member of the GDNF family was recently identified and designated persephin. Physiological responses to these neurotrophic factors require two receptor subunits, the novel glycosylphosphadidylinositol linked protein GFRα, and Ret receptor tyrosine kinase GFRbeta. Following the findings of GFRα,-1 and -2, a novel receptor in GFRα, family was identified from human and mouse and designated GFRα,-3. GFRα,-3 binds persephin, thus, persephin, GFRα,-3, and Ret PTK form a complex to transduce persephin signal and to mediate persephin function.

Poids moléculaire: Predicted: 44 kDa

Observed: 43 kDa

ID gène: 14587

NCBI Accession: NP_034410

UniProt: O35118