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ACIN1 anticorps (AA 760-810)

ACIN1 Reactivité: Humain WB, ELISA, ICC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6990317
  • Antigène Voir toutes ACIN1 Anticorps
    ACIN1 (Apoptotic Chromatin Condensation Inducer 1 (ACIN1))
    Épitope
    • 9
    • 8
    • 7
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 760-810
    Reactivité
    • 41
    • 22
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 37
    • 5
    Lapin
    Clonalité
    • 37
    • 5
    Polyclonal
    Conjugué
    • 35
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ACIN1 est non-conjugé
    Application
    • 33
    • 19
    • 9
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Purification
    Acinus Antibody is affinity chromatography purified via peptide column.
    Immunogène
    Acinus antibody was raised against a 35 amino acid peptide near the center of human Acinus. The immunogen is located within amino acids 760 - 810 of Acinus.
    Isotype
    IgG
    Top Product
    Discover our top product ACIN1 Anticorps primaire
  • Indications d'application
    Acinus antibody can be used for detection of Acinus by Western blot at 1 μ,g/mL. A 220 kDa band can be detected. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Acinus Antibody is supplied in PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,4 °C
    Stockage commentaire
    Acinus antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène
    ACIN1 (Apoptotic Chromatin Condensation Inducer 1 (ACIN1))
    Autre désignation
    Acinus (ACIN1 Produits)
    Synonymes
    anticorps acinus, anticorps acinusb, anticorps fi14c05, anticorps wu:fe06a10, anticorps wu:fi14c05, anticorps acinusa, anticorps acinusl, anticorps ik:tdsubc_2g5, anticorps si:zc14a17.12, anticorps wu:fb04g06, anticorps wu:fb40f03, anticorps wu:fb68h03, anticorps wu:fb80f07, anticorps wu:fc12e10, anticorps xx:tdsubc_2g5, anticorps acn, anticorps ACINUS, anticorps ACN, anticorps fSAP152, anticorps 2610036I19Rik, anticorps 2610510L13Rik, anticorps Acinus, anticorps Acn, anticorps C79325, anticorps acinusL, anticorps acinusS, anticorps mKIAA0670, anticorps apoptotic chromatin condensation inducer 1b, anticorps apoptotic chromatin condensation inducer 1a, anticorps apoptotic chromatin condensation inducer 1, anticorps apoptotic chromatin condensation inducer 1 S homeolog, anticorps acin1b, anticorps acin1a, anticorps acin1, anticorps ACIN1, anticorps acin1.S, anticorps Acin1
    Sujet
    Acinus Antibody: Chromatin condensation and nuclear fragmentation (CCNF) is the hallmark of apoptosis. CCNF is triggered by the activation of members of caspase family, caspase activated DNase (CAD/DFF40), and several novel proteins including AIF and CIDE. A new inducer of chromatin condensation was recently identified and designated Acinus (for apoptotic chromatin condensation inducer in the nucleus). Acinus is cleaved by caspase-3 and an additional unknown protease generating a small active peptide p17, which causes chromatin condensation in vitro when it is added to purified nuclei. Acinus also induces apoptotic chromatin condensation in cells. Acinus is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse and designated AcinusL, AcinusS and AcinusS'.
    Poids moléculaire
    220 kDa
    ID gène
    22985
    UniProt
    Q9UKV3
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