FAIM2 anticorps (N-Term)

N° du produit ABIN6990340

Détail du produit anti-FAIM2 anticorps

Antigène: FAIM2 (Fas Apoptotic Inhibitory Molecule 2 (FAIM2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAIM2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: FAIM2 Antibody is affinity chromatography purified via peptide column.

Immunogène: FAIM2 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human FAIM2. The immunogen is located within the first 50 amino acids of FAIM2.

Isotype: IgG

Information d'application

Indications d'application: FAIM2 antibody can be used for detection of FAIM2 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in mouse samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: FAIM2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: FAIM2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur FAIM2

Antigène: FAIM2 (Fas Apoptotic Inhibitory Molecule 2 (FAIM2))

Autre désignation: FAIM2 (FAIM2 Produits)

Synonymes: anticorps FAIM2, anticorps faim2, anticorps MGC84041, anticorps zgc:110143, anticorps MGC146456, anticorps LFG, anticorps LFG2, anticorps NGP35, anticorps NMP35, anticorps TMBIM2, anticorps 2900002L20Rik, anticorps Lfg, anticorps Lfg2, anticorps NMP25, anticorps Nmp35, anticorps Fas apoptotic inhibitory molecule 2, anticorps Fas apoptotic inhibitory molecule 2 L homeolog, anticorps Fas apoptotic inhibitory molecule 2a, anticorps fas apoptotic inhibitory molecule 2, anticorps FAIM2, anticorps faim2, anticorps faim2.L, anticorps faim2a, anticorps CpipJ_CPIJ015441, anticorps Faim2

Sujet: FAIM2 Antibody: Programmed cell death regulates a number of biological processes such as normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. FAIM2 is a recently identified protein that can inhibit the apoptotic signal transduced by the Fas receptor but not from the related tumor necrosis factor-alpha death signal. In this respect, FAIM2 is functionally similar to the anti-apoptotic proteins FAIM, FLIP and Bcl-xL. FAIM2, a seven membrane spanning protein, can bind the Fas receptor but does not regulate Fas expression or inhibit binding of FADD to Fas. FAIM2 is widely distributed, but highly expressed in the hippocampus and other neural tissues. FAIM2 was also identified as the neural membrane protein 35 (NMP35) and its expression is known to be regulated by the Phosphatidylinositol 3-kinase-Akt/PKB pathway.

ID gène: 23017

UniProt: Q9BWQ8