MAP1 anticorps

N° du produit ABIN6990393

Détail du produit anti-MAP1 anticorps

Antigène: MAP1 (Mannosidase Processing 1 (MAP1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: MAP1 Antibody is affinity chromatography purified via peptide column.

Immunogène: MAP-1 antibody was raised against a 15 amino acid synthetic peptide from near the center of human MAP-1. The immunogen is located within the last 50 amino acids of MAP1.

Isotype: IgG

Information d'application

Indications d'application: MAP1 antibody can be used for the detection of MAP-1 by Western blot at 1 to 4 μ,g/mL.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: MAP1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: MAP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur MAP1

Antigène: MAP1 (Mannosidase Processing 1 (MAP1))

Autre désignation: MAP1 (MAP1 Produits)

Synonymes: anticorps Map-1, anticorps Map1, anticorps mannosidase processing 1, anticorps Blood pressure QTL 196, anticorps Map1, anticorps Bp196

Sujet: MAP1 Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. Members of the Bcl-2 family are known to be critical regulators of this process. These proteins are characterized by the presence of several conserved motifs termed Bcl-2 homology (BH) domains. A related protein termed MAP-1 has recently been identified. This protein contains a BH3-like domain and induces caspase-dependent apoptosis in mammalian cells when overexpressed. It forms homodimers and associates with Bcl-2 family members such as Bax, Bcl-2, and Bcl-XL in vitro and in vivo. It has been suggested that MAP-1 associates with the tumor suppressor RASSF1A following death receptor activation, allowing a conformational change in Bax that leads to cellular apoptosis.

ID gène: 64112

NCBI Accession: NP_071434

UniProt: Q96BY2

Pathways: Positive Regulation of Endopeptidase Activity