CUL9 anticorps (C-Term)
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- Antigène Voir toutes CUL9 Anticorps
- CUL9 (Cullin 9 (CUL9))
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Épitope
- C-Term
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CUL9 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- Purification
- PARC Antibody is affinity chromatography purified via peptide column.
- Immunogène
- PARC antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human PARC. The immunogen is located within the last 50 amino acids of PARC.
- Isotype
- IgG
- Top Product
- Discover our top product CUL9 Anticorps primaire
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- Indications d'application
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PARC antibody can be used for the detection of PARC by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 1 μ,g/mL. For immunofluorescence start at 2 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PARC Antibody is supplied in PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,4 °C
- Stockage commentaire
- PARC antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Antigène
- CUL9 (Cullin 9 (CUL9))
- Autre désignation
- PARC (CUL9 Produits)
- Synonymes
- anticorps H7AP1, anticorps PARC, anticorps RP3-330M21.2, anticorps parc, anticorps 1810035I07Rik, anticorps Cul-9, anticorps Parc, anticorps mKIAA0708, anticorps RGD1562008, anticorps cullin-9, anticorps cullin 9, anticorps cullin-9, anticorps CUL9, anticorps LOC100083225, anticorps cul9, anticorps LOC100561099, anticorps Cul9
- Sujet
- PARC Antibody: The continued localization of p53 to the nucleus is essential for its function as a tumor suppressor. PARC, a large, Parkin-like ubiquitin ligase has recently been identified as a cytoplasmic anchor protein in p53-associated protein complexes. In the absence of stress, PARC inactivation results in nuclear localization of p53 and activation of p53-dependent apoptosis, while overexpression of this protein promoted cytoplasmic sequestration of p53. Surprisingly, PARC knockout mice were viable and exhibited no obvious phenotype, suggesting that other proteins, such as the highly related cullin family of E3 ubiquitin ligases, may perform similar functions in the absence of PARC. Additionally, it has been suggested that p53 binding to PARC may serve to control PARC function.
- ID gène
- 23113
- NCBI Accession
- NP_055904
- UniProt
- Q8IWT3
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