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CUL9 anticorps (C-Term)

CUL9 Reactivité: Humain, Souris WB, ELISA, ICC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6990433
  • Antigène Voir toutes CUL9 Anticorps
    CUL9 (Cullin 9 (CUL9))
    Épitope
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 18
    • 7
    • 2
    • 2
    Humain, Souris
    Hôte
    • 15
    • 4
    Lapin
    Clonalité
    • 15
    • 4
    Polyclonal
    Conjugué
    • 19
    Cet anticorp CUL9 est non-conjugé
    Application
    • 18
    • 9
    • 7
    • 7
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Purification
    PARC Antibody is affinity chromatography purified via peptide column.
    Immunogène
    PARC antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human PARC. The immunogen is located within the last 50 amino acids of PARC.
    Isotype
    IgG
    Top Product
    Discover our top product CUL9 Anticorps primaire
  • Indications d'application
    PARC antibody can be used for the detection of PARC by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 1 μ,g/mL. For immunofluorescence start at 2 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PARC Antibody is supplied in PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,4 °C
    Stockage commentaire
    PARC antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène
    CUL9 (Cullin 9 (CUL9))
    Autre désignation
    PARC (CUL9 Produits)
    Synonymes
    anticorps H7AP1, anticorps PARC, anticorps RP3-330M21.2, anticorps parc, anticorps 1810035I07Rik, anticorps Cul-9, anticorps Parc, anticorps mKIAA0708, anticorps RGD1562008, anticorps cullin-9, anticorps cullin 9, anticorps cullin-9, anticorps CUL9, anticorps LOC100083225, anticorps cul9, anticorps LOC100561099, anticorps Cul9
    Sujet
    PARC Antibody: The continued localization of p53 to the nucleus is essential for its function as a tumor suppressor. PARC, a large, Parkin-like ubiquitin ligase has recently been identified as a cytoplasmic anchor protein in p53-associated protein complexes. In the absence of stress, PARC inactivation results in nuclear localization of p53 and activation of p53-dependent apoptosis, while overexpression of this protein promoted cytoplasmic sequestration of p53. Surprisingly, PARC knockout mice were viable and exhibited no obvious phenotype, suggesting that other proteins, such as the highly related cullin family of E3 ubiquitin ligases, may perform similar functions in the absence of PARC. Additionally, it has been suggested that p53 binding to PARC may serve to control PARC function.
    ID gène
    23113
    NCBI Accession
    NP_055904
    UniProt
    Q8IWT3
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