TLR11 anticorps (C-Term)

N° du produit ABIN6990454

Détail du produit anti-TLR11 anticorps

Antigène: TLR11 (Tlr11) (Toll-Like Receptor 11 (Tlr11))

Épitope: C-Term

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLR11 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Purification: TLR11 Antibody is Ion exchange chromatography purified.

Immunogène: TLR11 antibody was raised against a peptide corresponding to 15 amino acids near the carboxy terminus of mouse TLR11. The immunogen is located within the last 50 amino acids of TLR11.

Isotype: IgG

Information d'application

Indications d'application: TLR11 antibody can be used for detection of TLR11 by Western blot at 0.5 to 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: TLR11 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: TLR11 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur TLR11

Antigène: TLR11 (Tlr11) (Toll-Like Receptor 11 (Tlr11))

Autre désignation: TLR11 (Tlr11 Produits)

Synonymes: anticorps RGD1564460, anticorps Gm287, anticorps toll-like receptor 11, anticorps Tlr11

Sujet: TLR11 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR11 is one of three mouse TLRs that lack a human ortholog. It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system.

ID gène: 239081

NCBI Accession: NP_991388

UniProt: Q6R5P0

Pathways: Activation of Innate immune Response