TICAM2 anticorps (C-Term)

N° du produit ABIN6990461

Détail du produit anti-TICAM2 anticorps

Antigène: TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TICAM2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purification: TIRP Antibody is Ion exchange chromatography purified.

Immunogène: TIRP antibody was raised against a peptide corresponding to amino acids near the C-terminus of human TIRP. The immunogen is located within the last 50 amino acids of TIRP.

Isotype: IgG

Information d'application

Indications d'application: TIRP antibody can be used for detection of TIRP by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human, mouse, and rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: TIRP Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: TIRP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur TICAM2

Antigène: TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))

Autre désignation: TIRP (TICAM2 Produits)

Synonymes: anticorps MyD88-4, anticorps TICAM-2, anticorps TIRAP3, anticorps TIRP, anticorps TRAM, anticorps B430113A10, anticorps Tirp, anticorps Trif, anticorps toll like receptor adaptor molecule 2, anticorps toll-like receptor adaptor molecule 2, anticorps TICAM2, anticorps Ticam2

Sujet: TIRP Antibody: TIRP is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TIRP, along with other molecules such as TRIF, MAL, and MyD88, serves as an adaptor protein that allows for the interaction and activation of the IL-1R-associated kinase (IRAK) family, the subsequent activation of TNF receptor associated factor (TRAF)-6, and ultimately the activation of NF-κ,B. Expression of TIRP appears to be essential for TLR4 signalling.

ID gène: 353376

UniProt: Q86XR7

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades