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ECSIT anticorps (C-Term)

ECSIT Reactivité: Humain, Souris WB, ELISA, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6990485
  • Antigène Voir toutes ECSIT Anticorps
    ECSIT
    Épitope
    • 8
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 290-340, C-Term
    Reactivité
    • 24
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 24
    • 2
    Lapin
    Clonalité
    • 24
    • 2
    Polyclonal
    Conjugué
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp ECSIT est non-conjugé
    Application
    • 24
    • 15
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    ECSIT Antibody is Ion exchange chromatography purified.
    Immunogène
    ECSIT antibody was raised against a peptide corresponding to 14 amino acids near the C-terminus of human ECSIT. The immunogen is located within amino acids 290 - 340 of ECSIT.
    Isotype
    IgG
    Top Product
    Discover our top product ECSIT Anticorps primaire
  • Indications d'application
    ECSIT antibody can be used for detection of ECSIT by Western blot at 0.5 to 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    ECSIT Antibody is supplied in PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,4 °C
    Stockage commentaire
    ECSIT antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène
    ECSIT
    Autre désignation
    ECSIT (ECSIT Produits)
    Synonymes
    anticorps CG10610, anticorps DmECSIT, anticorps Dmel\\CG10610, anticorps dECSIT, anticorps ECSIT, anticorps Sitpec, anticorps SITPEC, anticorps CG10610 gene product from transcript CG10610-RA, anticorps ECSIT signalling integrator, anticorps ecsit, anticorps ECSIT signalling integrator S homeolog, anticorps ECSIT, anticorps CpipJ_CPIJ003637, anticorps Ecsit, anticorps ecsit.S
    Sujet
    ECSIT Antibody: Activation of NF-κ,B as a result of Toll-like receptor (TLR) and IL-1 receptor signaling is a major component of innate immune responses. Signals from these receptors are relayed by a number of adapter molecules such as TRIF, TIRAP, and MyD88 to kinases such as IRAK and other intermediates such as TNF receptor associated factor (TRAF)-6. ECSIT (evolutionarily conserved signaling intermediate in Toll pathways) was initially identified as a cytoplasmic protein interacting specifically with TNF receptor associated factor (TRAF)-6 in the TLR pathway. Recently however, ECSIT has also been shown to be required for bone morphogenetic protein (Bmp) signaling and mesoderm formation during mouse embryogenesis, indicating the possibility of cross-talk between the TLR/IL-B and Bmp signaling pathways.
    ID gène
    51295
    NCBI Accession
    NP_057665
    UniProt
    Q9BQ95
    Pathways
    Signalisation TLR, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome
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