ECSIT anticorps (C-Term)
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- Antigène Voir toutes ECSIT Anticorps
- ECSIT
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Épitope
- AA 290-340, C-Term
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ECSIT est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- ECSIT Antibody is Ion exchange chromatography purified.
- Immunogène
- ECSIT antibody was raised against a peptide corresponding to 14 amino acids near the C-terminus of human ECSIT. The immunogen is located within amino acids 290 - 340 of ECSIT.
- Isotype
- IgG
- Top Product
- Discover our top product ECSIT Anticorps primaire
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- Indications d'application
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ECSIT antibody can be used for detection of ECSIT by Western blot at 0.5 to 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- ECSIT Antibody is supplied in PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,4 °C
- Stockage commentaire
- ECSIT antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Antigène
- ECSIT
- Autre désignation
- ECSIT (ECSIT Produits)
- Synonymes
- anticorps CG10610, anticorps DmECSIT, anticorps Dmel\\CG10610, anticorps dECSIT, anticorps ECSIT, anticorps Sitpec, anticorps SITPEC, anticorps CG10610 gene product from transcript CG10610-RA, anticorps ECSIT signalling integrator, anticorps ecsit, anticorps ECSIT signalling integrator S homeolog, anticorps ECSIT, anticorps CpipJ_CPIJ003637, anticorps Ecsit, anticorps ecsit.S
- Sujet
- ECSIT Antibody: Activation of NF-κ,B as a result of Toll-like receptor (TLR) and IL-1 receptor signaling is a major component of innate immune responses. Signals from these receptors are relayed by a number of adapter molecules such as TRIF, TIRAP, and MyD88 to kinases such as IRAK and other intermediates such as TNF receptor associated factor (TRAF)-6. ECSIT (evolutionarily conserved signaling intermediate in Toll pathways) was initially identified as a cytoplasmic protein interacting specifically with TNF receptor associated factor (TRAF)-6 in the TLR pathway. Recently however, ECSIT has also been shown to be required for bone morphogenetic protein (Bmp) signaling and mesoderm formation during mouse embryogenesis, indicating the possibility of cross-talk between the TLR/IL-B and Bmp signaling pathways.
- ID gène
- 51295
- NCBI Accession
- NP_057665
- UniProt
- Q9BQ95
- Pathways
- Signalisation TLR, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome
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