CBLN1 anticorps (C-Term)

N° du produit ABIN6990561

Détail du produit anti-CBLN1 anticorps

Antigène: CBLN1 (Cerebellin 1 Precursor (CBLN1))

Épitope: C-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CBLN1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Purification: Precerebellin Antibody is affinity chromatography purified via peptide column.

Immunogène: Precerebellin antibody was raised against a 16 amino acid synthetic peptide from near the carboxy- terminus human precerebellin. The immunogen is located within the last 50 amino acids of Precerebellin.

Isotype: IgG

Information d'application

Indications d'application: Precerebellin antibody can be used for the detection of precerebellin by Western blot at 2 - 4 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunocytochemistry in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Precerebellin Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: Precerebellin antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur CBLN1

Antigène: CBLN1 (Cerebellin 1 Precursor (CBLN1))

Autre désignation: Precerebellin (CBLN1 Produits)

Synonymes: anticorps cbln1, anticorps zgc:92807, anticorps CBLN1, anticorps MGC145915, anticorps AI323299, anticorps cerebellin 3 precursor, anticorps cerebellin 1 precursor, anticorps cerebellin 1 precursor L homeolog, anticorps cerebellin 1 precursor protein, anticorps cbln3, anticorps cbln1, anticorps cbln1.L, anticorps CBLN1, anticorps Cbln1

Sujet: Precerebellin Antibody: Precerebellin is the precursor of the brain-specific hexadecapeptide cerebellin, a protein with substantial similarity to the globular region of the B chain of complement component C1q. Cerebellin exerts neuromodulatory functions by directly stimulating norepinephrine release via the adenylate cyclase/pka- dependent signaling pathway, and indirectly enhances adrenocortical secretion in vivo, through a paracrine mechanism involving medullary catecholamine release. The active form of precerebellin is highly enriched in postsynaptic structures of cerebellar Purkinje cells in cartwheel neurons of the dorsal cochlear nucleus. Because precerebellin belongs to the C1q/tumor necrosis factor superfamily of secreted proteins and has similarity to adiponectin and CTRP3, it has been suggested that precerebellin posseses functions other than those already stated.

ID gène: 869

UniProt: P23435