ARHGEF17 anticorps (AA 910-960)

N° du produit ABIN6990812

Détail du produit anti-ARHGEF17 anticorps

Antigène: ARHGEF17 (rho Guanine Nucleotide Exchange Factor (GEF) 17 (ARHGEF17))

Épitope: AA 910-960

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGEF17 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: TEM4 Antibody is affinity chromatography purified via peptide column.

Immunogène: TEM4 antibody was raised against a 18 amino acid synthetic peptide near the center of human TEM4. The immunogen is located within amino acids 910 - 960 of TEM4.

Isotype: IgG

Information d'application

Indications d'application: TEM4 antibody can be used for detection of TEM4 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: TEM4 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: TEM4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur ARHGEF17

Antigène: ARHGEF17 (rho Guanine Nucleotide Exchange Factor (GEF) 17 (ARHGEF17))

Autre désignation: TEM4 (ARHGEF17 Produits)

Synonymes: anticorps P164RHOGEF, anticorps TEM4, anticorps p164-RhoGEF, anticorps 8030463K16, anticorps AI428794, anticorps AW558066, anticorps BC035332, anticorps mKIAA0337, anticorps Rho guanine nucleotide exchange factor 17, anticorps Rho guanine nucleotide exchange factor (GEF) 17, anticorps ARHGEF17, anticorps Arhgef17

Sujet: TEM4 Antibody: Rho GTPases, which are activated by specific guanine-nucleotide exchange factors (GEFs), play pivotal roles in several cellular functions. TEM4, encoding a protein containing 1510 amino acids, contains a RhoGEF-specific Dbl homology (DH) domain but lacks their typical pleckstrin homology domain. TEM4 is a Rho-specific GEF with novel structural and regulatory properties and predominant expression in the heart. It couples tyrosine kinase signals with the activation of the rho/rac GTPases, thus leading to cell differentiation and/or proliferation. Elevated levels of TEM4, TEM5, TEM6, TEM7 and TEM7R were also raised in breast cancer tissues. TEM4 could also prove to be useful targets therapeutically.

Poids moléculaire: Predicted: 220 kDa

Observed: 200 kDa

ID gène: 9828

UniProt: Q96PE2