VPS53 anticorps (C-Term)

N° du produit ABIN6990900

Détail du produit anti-VPS53 anticorps

Antigène: VPS53 (Vacuolar Protein Sorting 53 Homolog (VPS53))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VPS53 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Purification: VPS53 Antibody is affinity chromatography purified via peptide column.

Immunogène: VPS53 antibody was raised against a 18 amino acid synthetic peptide from near the carboxy terminus of human VPS53. The immunogen is located within the last 50 amino acids of VPS53.

Isotype: IgG

Information d'application

Indications d'application: VPS53 antibody can be used for detection of VPS53 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 2.5 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: VPS53 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: VPS53 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur VPS53

Antigène: VPS53 (Vacuolar Protein Sorting 53 Homolog (VPS53))

Autre désignation: VPS53 (VPS53 Produits)

Synonymes: anticorps wu:fb77d11, anticorps zgc:103741, anticorps DKFZp469N152, anticorps 2010002A08Rik, anticorps 2310040I21Rik, anticorps 3100002B05Rik, anticorps Hccs1, anticorps HCCS1, anticorps hVps53L, anticorps pp13624, anticorps RGD1311391, anticorps VPS53, GARP complex subunit, anticorps vacuolar protein sorting 53 homolog (S. cerevisiae), anticorps vacuolar protein sorting 53, anticorps VPS53 GARP complex subunit, anticorps VPS53, anticorps vps53, anticorps PAAG_00802, anticorps MCYG_06020, anticorps VDBG_07188, anticorps MGYG_05943, anticorps Vps53

Sujet: VPS53 Antibody: The sorting of acid hydrolases to lysosomes rely on mannose 6-phosphate receptors that cycle between the trans-Golgi network (TGN) and endosomes. The maintenance of this cycle requires the function of the mammalian Golgi-associated retrograde protein (GARP) complex which is composed of three subunits: VPS52, VPS53, and VPS54. Depletion of any of these three proteins, such as by RNAi, impairs the retrograde transport of multiple TGN proteins. VPS53 was identified as an HIV dependency factor (HDF) and plays a role in viral entry to the cell, suggesting that VPS53 may be an important drug target in HIV treatment. At least five isoforms of VPS53 are known to exist.

ID gène: 55275

UniProt: Q5VIR6