DLGAP1 anticorps (AA 640-690)

N° du produit ABIN6990914

Détail du produit anti-DLGAP1 anticorps

Antigène: DLGAP1 (Discs, Large (Drosophila) Homolog-Associated Protein 1 (DLGAP1))

Épitope: AA 640-690

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DLGAP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: At least three isoforms of SAPAP1 are known to exist. This SAPAP1 antibody will not cross-react with other SAPAP proteins.

Purification: SAPAP1 Antibody is affinity chromatography purified via peptide column.

Immunogène: SAPAP1 antibody was raised against a 18 amino acid synthetic peptide from near the center of human SAPAP1. The immunogen is located within amino acids 640 - 690 of SAPAP1.

Isotype: IgG

Information d'application

Indications d'application: SAPAP1 antibody can be used for detection of SAPAP1 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: SAPAP1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: SAPAP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur DLGAP1

Antigène: DLGAP1 (Discs, Large (Drosophila) Homolog-Associated Protein 1 (DLGAP1))

Autre désignation: SAPAP1 (DLGAP1 Produits)

Synonymes: anticorps DKFZp469D0713, anticorps gkap, anticorps sapap1, anticorps DAP-1, anticorps DAP-1-ALPHA, anticorps DAP-1-BETA, anticorps GKAP, anticorps SAPAP1, anticorps hGKAP, anticorps 4933422O14Rik, anticorps 9630002F18, anticorps AI845682, anticorps AI848168, anticorps BB075781, anticorps D17Bwg0511e, anticorps GKAP/SAPAP, anticorps GKPA/SAPAP, anticorps Gkap, anticorps Sapap1, anticorps mKIAA4162, anticorps DLG associated protein 1, anticorps discs, large (Drosophila) homolog-associated protein 1, anticorps disks large-associated protein 1, anticorps discs, large homolog-associated protein 1, anticorps discs, large (Drosophila) homolog-associated protein 1b, anticorps DLGAP1, anticorps LOC100408093, anticorps LOC100548434, anticorps dlgap1, anticorps Dlgap1, anticorps dlgap1b

Sujet: SAPAP1 Antibody: SAP90/PSD-95-associated protein 1 (SAPAP1, also known as DLGAP1 or GKAP) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP1 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2). SAPAP1 mRNA is targeted to cell bodies in a similar manner to SAPAP2 and -4, whereas SAPAP3 mRNA is detected mainly in cell bodies. SAPAP1 protein however, is targeted to the synapse and is not reliant on the synaptic localization of PSD-95 or the synaptic scaffolding molecule (S-SCAM).

ID gène: 9229

NCBI Accession: NP_004737

UniProt: O60500