MEX3C anticorps (C-Term)

N° du produit ABIN6991001

Détail du produit anti-MEX3C anticorps

Antigène: MEX3C (Mex-3 Homolog C (C. Elegans) (MEX3C))

Épitope: AA 540-590, C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MEX3C est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Rkhd2 Antibody is affinity chromatography purified via peptide column.

Immunogène: Rkhd2 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human RKHD2. The immunogen is located within amino acids 540 - 590 of Rkhd2.

Isotype: IgG

Information d'application

Indications d'application: Rkhd2 antibody can be used for detection of Rkhd2 by Western blot at 0.5 - 1 μ,g/mL.

Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rkhd2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: Rkhd2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur MEX3C

Antigène: MEX3C (Mex-3 Homolog C (C. Elegans) (MEX3C))

Autre désignation: Rkhd2 (MEX3C Produits)

Synonymes: anticorps Rkhd2, anticorps RKHD2, anticorps rkhd2, anticorps bm-013, anticorps rnf194, anticorps MEX-3C, anticorps RNF194, anticorps A130001D14Rik, anticorps BC035207, anticorps BM-013, anticorps mex-3 RNA binding family member C, anticorps mex3 RNA binding family member C, anticorps Mex3c, anticorps MEX3C, anticorps mex3c

Sujet: Rkhd2 Antibody: Rkhd2, also known as MEX3C is a member of a novel family of four homologous human MEX3 proteins each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module. MEX3 proteins, including Rkhd2, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and the cytoplasm via the CRM1 export pathway. These proteins are a novel family of evolutionarily conserved RNA-binding proteins, differentially recruited to P bodies and potentially involved in post-transcriptional regulatory mechanisms. It has been suggested that genetic variations in Rkhd2 may be associated with susceptibility to essential hypertension type 8. Rkhd3 and Rkhd4, but not Rkhd2, co-localize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), recently characterized as centers of mRNA turnover.

ID gène: 51320

NCBI Accession: NP_057710

UniProt: Q5U5Q3