MEX3A anticorps (C-Term)

N° du produit ABIN6991005

Détail du produit anti-MEX3A anticorps

Antigène: MEX3A (Mex-3 Homolog A (MEX3A))

Épitope: AA 420-470, C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MEX3A est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purification: Rkhd4 Antibody is affinity chromatography purified via peptide column.

Immunogène: Rkhd4 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human Rkhd4. The immunogen is located within amino acids 420 - 470 of Rkhd4.

Isotype: IgG

Information d'application

Indications d'application: Rkhd4 antibody can be used for detection of Rkhd4 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rkhd4 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: Rkhd4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur MEX3A

Antigène: MEX3A (Mex-3 Homolog A (MEX3A))

Autre désignation: Rkhd4 (MEX3A Produits)

Synonymes: anticorps RKHD4, anticorps MEX-3A, anticorps 2700083E18Rik, anticorps Gm411, anticorps Rkhd4, anticorps mex-3 RNA binding family member A, anticorps mex-3 RNA binding family member A L homeolog, anticorps mex3 RNA binding family member A, anticorps MEX3A, anticorps mex3a.L, anticorps Mex3a

Sujet: Rkhd4 Antibody: Rkhd4, also known as MEX3A is a member of a novel family of four homologous human MEX3 proteins each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module. MEX3 proteins, including Rkhd4, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and the cytoplasm via the CRM1 export pathway. These proteins are a novel family of evolutionarily conserved RNA-binding proteins, differentially recruited to P bodies and potentially involved in post-transcriptional regulatory mechanisms. While Rkhd2 has been suggested to be associated with susceptibility to essential hypertension type 8, the function of Rkhd4 remains unknown. Rkhd3 and Rkhd4, but not Rkhd2, co-localize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), recently characterized as centers of mRNA turnover.

ID gène: 92312

UniProt: A1L020