RCAN2 anticorps (AA 70-120)

N° du produit ABIN6991070

Détail du produit anti-RCAN2 anticorps

Antigène: RCAN2 (Regulator of Calcineurin 2 (RCAN2))

Épitope: AA 70-120

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RCAN2 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purification: RCAN2 Antibody is affinity chromatography purified via peptide column.

Immunogène: RCAN2 antibody was raised against a 14 amino acid synthetic peptide near the center of human RCAN2. The immunogen is located within amino acids 70 - 120 of RCAN2.

Isotype: IgG

Information d'application

Indications d'application: RCAN2 antibody can be used for detection of RCAN2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: RCAN2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: RCAN2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur RCAN2

Antigène: RCAN2 (Regulator of Calcineurin 2 (RCAN2))

Autre désignation: RCAN2 (RCAN2 Produits)

Synonymes: anticorps DSCR1L1, anticorps si:ch211-124g24.1, anticorps zgc:85746, anticorps RCAN2, anticorps DKFZp459H071, anticorps rcan2, anticorps CSP2, anticorps MCIP2, anticorps RCN2, anticorps ZAKI-4, anticorps ZAKI4, anticorps Csp2, anticorps Dscr1l1, anticorps Dcip2, anticorps Zaki-4, anticorps regulator of calcineurin 2, anticorps rcan2, anticorps RCAN2, anticorps Rcan2

Sujet: RCAN2 Antibody: Regulator of calcineurin 2 (RCAN2), also known as ZAKI4 and DSCR1L1, is expressed as two isoforms differing at their N-terminus. The longer of the two (isoform 1) is expressed exclusively in the brain, while isoform 2 is ubiquitously expressed, with highest expression in brain, heart, and muscle. Both isoforms bind to the catalytic subunit of calcineurin, a Ca++-dependent protein phosphatase involved in several neuronal functions, though their C-terminal region and inhibit calcineurin's activity. Unlike isoform 1 of RCAN2, the expression of the second isoform is not induced by the thyroid hormone T3. RCAN2 is a member of a family of three endogenous calcineurin regulators that are located near the minimal supernumerary fragment of chromosome 21 in individuals with Down syndrome, suggesting that they play a role in this syndrome. Multiple isoforms of RCAN2 are known to exist.

ID gène: 53901

UniProt: Q9JHG2