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JMJD1C anticorps (N-Term)

JMJD1C Reactivité: Humain, Souris, Rat ELISA, WB, IHC (p), IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6991178
  • Antigène Voir toutes JMJD1C Anticorps
    JMJD1C (Jumonji Domain Containing 1C (JMJD1C))
    Épitope
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 380-430, N-Term
    Reactivité
    • 13
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 10
    • 3
    Lapin
    Clonalité
    • 10
    • 3
    Polyclonal
    Conjugué
    • 9
    • 2
    • 1
    • 1
    Cet anticorp JMJD1C est non-conjugé
    Application
    • 7
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Specificité
    This antibody will not cross-react with JMJD1A or JMJD1B.
    Purification
    JMJD1C Antibody is affinity chromatography purified via peptide column.
    Immunogène
    JMJD1C antibody was raised against a 20 amino acid synthetic peptide from near the amino terminus of human JMJD1C. The immunogen is located within amino acids 380 - 430 of JMJD1C.
    Isotype
    IgG
    Top Product
    Discover our top product JMJD1C Anticorps primaire
  • Indications d'application
    JMJD1C antibody can be used for detection of JMJD1C by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    JMJD1C Antibody is supplied in PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,4 °C
    Stockage commentaire
    JMJD1C antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène
    JMJD1C (Jumonji Domain Containing 1C (JMJD1C))
    Autre désignation
    JMJD1C (JMJD1C Produits)
    Synonymes
    anticorps RP11-10C13.2, anticorps TRIP8, anticorps 5430433L24Rik, anticorps D630035I23Rik, anticorps Jmjdic, anticorps Pr2, anticorps JMJD1C, anticorps DKFZp469A034, anticorps jumonji domain containing 1C, anticorps JMJD1C, anticorps Jmjd1c, anticorps jmjd1c
    Sujet
    JMJD1C Antibody: The jumonji domain containing 1C protein (JMJD1C) was initially discovered in silico, and later suggested to be a candidate gene for autism. Like the related proteins JMJD1A and JMJD1B, JMJD1C is a histone H3K9 demethylase implicated in the nuclear hormone receptor-based transcriptional regulation. JMJD1C mRNA is highly expressed in undifferentiated embryonic stem (ES) cells as well as pancreatic islet, diffuse-type gastric cancer, and other tissues and tumors. The JMJD1C gene promoter contain bHLH-, AP-1-, and POU5F1-binding sites, and as preferential expression of POU5F1 has been reported in ES cells, pancreatic islet, and diffuse-type gastric cancer, it has been suggested that POU5F1-mediated expression of JMJD1C reactivates previously silenced genes in ES cells and diffuse-type gastric cancer. At least three isoforms of JMJD1C are known to exist.
    ID gène
    221037
    NCBI Accession
    NP_116165
    UniProt
    Q15652
    Pathways
    Nuclear Hormone Receptor Binding
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