ANKRD27 anticorps (AA 640-690)

N° du produit ABIN6991210

Détail du produit anti-ANKRD27 anticorps

Antigène: ANKRD27 (Ankyrin Repeat Domain 27 (VPS9 Domain) (ANKRD27))

Épitope: AA 640-690

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANKRD27 est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: VARP Antibody is affinity chromatography purified via peptide column.

Immunogène: VARP antibody was raised against a 15 amino acid synthetic peptide near the center of human VARP. The immunogen is located within amino acids 640 - 690 of VARP.

Isotype: IgG

Information d'application

Indications d'application: VARP antibody can be used for detection of VARP by Immunohistochemistry at 5 μ,g/mL.

Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: VARP Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: VARP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur ANKRD27

Antigène: ANKRD27 (Ankyrin Repeat Domain 27 (VPS9 Domain) (ANKRD27))

Autre désignation: VARP (ANKRD27 Produits)

Synonymes: anticorps VARP, anticorps AA408090, anticorps BC016493, anticorps D330003H11Rik, anticorps Varp, anticorps ankyrin repeat domain 27, anticorps ankyrin repeat domain 27 (VPS9 domain), anticorps ANKRD27, anticorps Ankrd27

Sujet: VARP Antibody: The VPS9 ankyrin repeat protein (VARP) binds to the Rab21, a guanine nucleotide exchange factor that plays an essential role in endocytic trafficking. VARP localizes to early endosomes and is thought to regulate endosome dynamics. VARP also interacts with TI-VAMP/VAMP7, a vesicular SNARE that mediates an exocytic pathway that is crucial to neurite growth. Depletion of VARP by RNA interference impairs neurite growth, suggesting that VARP is a positive regulator of neurite growth.

ID gène: 84079

NCBI Accession: NP_115515

UniProt: Q96NW4