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TMEM38A anticorps (C-Term)

TMEM38A Reactivité: Humain, Rat, Souris WB, ELISA, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6991239
  • Antigène Voir toutes TMEM38A Anticorps
    TMEM38A (Transmembrane Protein 38A (TMEM38A))
    Épitope
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 8
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Rat, Souris
    Hôte
    • 8
    • 1
    Lapin
    Clonalité
    • 9
    Polyclonal
    Conjugué
    • 9
    Cet anticorp TMEM38A est non-conjugé
    Application
    • 9
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Purification
    TMEM38A Antibody is affinity chromatography purified via peptide column.
    Immunogène
    TMEM38A antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human TMEM38A. The immunogen is located within the last 50 amino acids of TMEM38A.
    Isotype
    IgG
    Top Product
    Discover our top product TMEM38A Anticorps primaire
  • Indications d'application
    TMEM38A antibody can be used for detection of TMEM38A by Western blot at 1 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in rat samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    TMEM38A Antibody is supplied in PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,4 °C
    Stockage commentaire
    TMEM38A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène
    TMEM38A (Transmembrane Protein 38A (TMEM38A))
    Autre désignation
    TMEM38A (TMEM38A Produits)
    Synonymes
    anticorps zgc:77831, anticorps MGC75707, anticorps TMEM38A, anticorps TRIC-A, anticorps TRICA, anticorps 1110001E17Rik, anticorps AI413399, anticorps mg33a, anticorps RGD1307901, anticorps Srp-27, anticorps transmembrane protein 38A, anticorps transmembrane protein 38a, anticorps transmembrane protein 38A L homeolog, anticorps tmem38a, anticorps CpipJ_CPIJ011791, anticorps CpipJ_CPIJ013655, anticorps TMEM38A, anticorps Tmem38a, anticorps tmem38a.L
    Sujet
    TMEM38A Antibody: TMEM38A and TMEM38B are two recently identified trimeric intracellular cation (TRIC) channel subtypes. TMEM38A is preferentially expressed in excitable tissues such as striated muscle and brain and localizes to the sarcoplasmic reticulum (SR) in muscle tissues. Mice deficient in both TMEM38A and TMEM38B suffer embryonic cardiac failure, the cardiac myocytes display severe dysfunction in SR Ca2+ handling, weakened Ca2+ release, and reduced K+ permeability indicating that the TRIC cation channels are likely to act as counter-ion channels that function in synchronization with Ca2+ release from intracellular stores. Other experiments have shown that TMEM38A and TMEM38B can act with junctophilin proteins to support efficient ryanodine receptor-mediated Ca2+ release in muscle cells.
    ID gène
    79041
    UniProt
    Q9H6F2
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