SLFN12 anticorps (C-Term)

N° du produit ABIN6991244

Détail du produit anti-SLFN12 anticorps

Antigène: SLFN12 (Schlafen Family Member 12 (SLFN12))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLFN12 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: SLFN12 Antibody is affinity chromatography purified via peptide column.

Immunogène: SLFN12 antibody was raised against a 12 amino acid synthetic peptide from near the carboxy terminus human SLFN12. The immunogen is located within the last 50 amino acids of SLFN12.

Isotype: IgG

Information d'application

Indications d'application: SLFN12 antibody can be used for detection of SLFN12 by Western blot at 1 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: SLFN12 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: SLFN12 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur SLFN12

Antigène: SLFN12 (Schlafen Family Member 12 (SLFN12))

Autre désignation: SLFN12 (SLFN12 Produits)

Synonymes: anticorps SLFN3, anticorps SLFN12L, anticorps schlafen family member 12, anticorps SLFN12

Sujet: SLFN12 Antibody: Despite being first described several years ago, the roles of the Schlafen (SLFN) family of proteins remain largely unknown. The SLFN genes are preferentially expressed in lymphoid tissues and differentially regulated during thymocyte maturation. It is thought that many play roles in cell growth, hemopoietic cell differentiation, and T cell development and maturation. Most members contain at least one divergent AAA domain (AAA_4) that may play a role in ATP binding. Although also known as SLFN3, a Schlafen family member that may be a marker of T cell activation, human SLFN12 has relatively low homology to SLFN3 in other species. Loss of the SLFN12 gene due to deletion is associated with Kabuki syndrome, a multiple congenital anomaly syndrome, suggesting SLFN may play a role in this genetic condition.

ID gène: 55106

NCBI Accession: NP_060512

UniProt: Q8IYM2