EFHD2 anticorps (N-Term)

N° du produit ABIN6991298

Détail du produit anti-EFHD2 anticorps

Antigène: EFHD2 (EF-Hand Domain Family, Member D2 (EFHD2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EFHD2 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purification: EFHD2 Antibody is affinity chromatography purified via peptide column.

Immunogène: EFHD2 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human EFHD2. The immunogen is located within the first 50 amino acids of EFHD2.

Isotype: IgG

Information d'application

Indications d'application: EFHD2 antibody can be used for detection of EFHD2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: EFHD2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: EFHD2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Références pour anticorps anti-EFHD2 (ABIN6991298)

ODonnell, Dagley, Curley, Darbey, OShaughnessy, Diemer, Pilatz, Fietz, Stanton, Smith, Rebourcet: "Sertoli cell-enriched proteins in mouse and human testicular interstitial fluid." dans: PloS one, Vol. 18, Issue 9, pp. e0290846, (2023) (PubMed).

Détails sur EFHD2

Antigène: EFHD2 (EF-Hand Domain Family, Member D2 (EFHD2))

Autre désignation: EFHD2 (EFHD2 Produits)

Synonymes: anticorps SWS1, anticorps efhd2, anticorps EFHD2, anticorps MGC131292, anticorps 2600015J22Rik, anticorps AA408606, anticorps D4Wsu27e, anticorps si:dkey-72l14.9, anticorps wu:fb80e07, anticorps EF-hand domain family member D2, anticorps EF-hand domain family, member D2, anticorps EF-hand domain family member D2 L homeolog, anticorps EF hand domain containing 2, anticorps EFHD2, anticorps Efhd2, anticorps efhd2, anticorps efhd2.L

Sujet: EFHD2 Antibody: EFHD2, also known as Swiprosin-1 or SWS1, is an EF-hand and coiled-coil-containing adaptor protein that plays a role in lymphocyte physiology. EFHD2 exhibits the highest expression in CD8+ T cells and immature B cells. It provides a membrane scaffold that is required for the Syk-, SLP-65-, and PLCgamma2-dependent B-cell receptor (BCR)-induced calcium flux. EFHD2 may also regulate BCR-induced immature and primary B-cell apoptosis. It controls spontaneous apoptosis through the regulation of BCL2L1 abundance. Also, EFHD2 plays a role as negative regulator of the canonical NF-κ,B-activating branch.

ID gène: 79180

NCBI Accession: NP_077305

UniProt: Q96C19