TMEM184C anticorps (C-Term)

N° du produit ABIN6991312

Détail du produit anti-TMEM184C anticorps

Antigène: TMEM184C (Transmembrane Protein 184C (TMEM184C))

Épitope: AA 340-390, C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMEM184C est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: TMEM184C Antibody is affinity chromatography purified via peptide column.

Immunogène: TMEM184C antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human TMEM184C. The immunogen is located within amino acids 340 - 390 of TMEM184C.

Isotype: IgG

Information d'application

Indications d'application: TMEM184C antibody can be used for detection of TMEM184C by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: TMEM184C Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: TMEM184C antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur TMEM184C

Antigène: TMEM184C (Transmembrane Protein 184C (TMEM184C))

Autre désignation: TMEM184C (TMEM184C Produits)

Synonymes: anticorps TMEM34, anticorps 8430433H16Rik, anticorps AI645453, anticorps AL033298, anticorps BC004056, anticorps Tmem34, anticorps transmembrane protein 184C, anticorps transmembrane protein 184C L homeolog, anticorps TMEM184C, anticorps Tmem184c, anticorps tmem184c.L

Sujet: TMEM184C Antibody: Anaplastic thyroid cancer is one of the most lethal forms of cancer, but the precise carcinogenic mechanism has not been identified. TMEM184C, also known as TMEM34, was identified in a cDNA microarray analysis as being down-regulated in anaplastic thyroid cancers compared to normal thyroid tissues. TMEM184C protein expression was also lower in cell lines derived from these types of cancers compared to that of normal thyroid tissues or cell lines based on other types of thyroid cancers. Furthermore, transfection of TMEM34 into KTA2 cells led to the inhibition of cell growth, suggesting that TMEM184C might act as a tumor suppressor in anaplastic thyroid cancers.

ID gène: 55751

NCBI Accession: NP_060711

UniProt: Q9NVA4