ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
Purification
FREM2 Antibody is affinity chromatography purified via peptide column.
Immunogène
FREM2 antibody was raised against a 19 amino acid synthetic peptide near the center of human FREM2. The immunogen is located within amino acids 1920 - 1970 of FREM2.
FREM2
Reactivité: Humain
ELISA, WB, IF, IC
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
FREM2 antibody was raised against a 19 amino acid peptide near the center of human FREM2. Antibody can also be used for immunocytochemistry starting at 20 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
FREM2 Antibody is supplied in PBS containing 0.02 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C,4 °C
Stockage commentaire
FREM2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antigène
FREM2
(Fras1 Related Extracellular Matrix Protein 2 (FREM2))
anticorps 6030440P17Rik, anticorps 8430406N05Rik, anticorps Gm409, anticorps b2b1562Clo, anticorps my, anticorps ne, anticorps nv1, anticorps RGD1566012, anticorps FRAS1 related extracellular matrix protein 2, anticorps Fras1 related extracellular matrix protein 2, anticorps FREM2, anticorps Frem2
Sujet
FREM2 Antibody: FREM2 is a member of the FRAS1-related extracellular matrix protein family and like FREM1, mutations in the FREM2 gene are associated with Fraser syndrome. FREM2 localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions during morphogenetic processes and is thought to be required for maintaining the integrity of the skin epithelium and the differentiated state of renal epithelia. The FREM2 gene is one of several genes whose transcription is affecteded by TFAP2C, a transcription factor involved in mammary development, differentiation, and oncogenesis.