Secernin 1 anticorps (C-Term)

N° du produit ABIN6991376

Détail du produit anti-Secernin 1 anticorps

Antigène: Secernin 1 (SCRN1)

Épitope: AA 320-370, C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Secernin 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purification: SCRN1 Antibody is affinity chromatography purified via peptide column.

Immunogène: SCRN1 antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human SCRN1. The immunogen is located within amino acids 320 - 370 of SCRN1.

Isotype: IgG

Information d'application

Indications d'application: SCRN1 antibody can be used for detection of SCRN1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: SCRN1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: SCRN1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur Secernin 1

Antigène: Secernin 1 (SCRN1)

Autre désignation: SCRN1 (SCRN1 Produits)

Synonymes: anticorps MGC84738, anticorps SES1, anticorps 2810019K23Rik, anticorps 6330535A03Rik, anticorps AI852905, anticorps mKIAA0193, anticorps secernin 1, anticorps secernin 1 L homeolog, anticorps SCRN1, anticorps scrn1.L, anticorps Scrn1

Sujet: SCRN1 Antibody: SCRN1 was first identified as a cytosolic protein that is involved in the regulation of exocytosis from peritoneal mast cells. More recent studies have shown that SCRN1 expression is upregulated in gastric cancer cell lines and may possess epitopes that could function as tumor-associated antigens, potentially providing targets for cancer vaccines in the treatment of gastric cancers. Another report indicates that decreased expression of SCRN1 via RNAi expression resulted in significantly lower rates of cell growth in colorectal cancer cell lines, and increased SCRN1 expression in patients with colorectal cancer correlated with poor prognosis, suggesting that SCRN1 may also be involved in the regulation of cell growth and might be useful as a prognostic tool.

ID gène: 9805

NCBI Accession: NP_001138985

UniProt: Q12765