EFCAB4B anticorps (C-Term)

N° du produit ABIN6991440

Détail du produit anti-EFCAB4B anticorps

Antigène: EFCAB4B (EF-Hand Calcium Binding Domain 4B (EFCAB4B))

Épitope: AA 640-690, C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EFCAB4B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: EFCAB4B Antibody is affinity chromatography purified via peptide column.

Immunogène: EFCAB4B antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human EFCAB4B. The immunogen is located within amino acids 640 - 690 of EFCAB4B.

Isotype: IgG

Information d'application

Indications d'application: EFCAB4B antibody can be used for detection of EFCAB4B by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: EFCAB4B Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: EFCAB4B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur EFCAB4B

Antigène: EFCAB4B (EF-Hand Calcium Binding Domain 4B (EFCAB4B))

Autre désignation: EFCAB4B (EFCAB4B Produits)

Synonymes: anticorps CRACR2A, anticorps Gm1073, anticorps Gm462, anticorps calcium release activated channel regulator 2A, anticorps CRACR2A, anticorps Cracr2a

Sujet: EFCAB4B Antibody: EFCAB4B, also known as Calcium release-activated calcium channel regulator 2A, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation. EFCAB4B acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration. A closely related protein, EFCAB4A, is likely to play a similar role as EFCAB4B, but the detailed function of EFCAB4A is still under investigation.

ID gène: 84766

NCBI Accession: NP_001138430

UniProt: Q9BSW2